PDZ and LIM domain protein 4 is a protein that in humans is encoded by the PDLIM4gene.[1][2]
References
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Cuppen E, van Ham M, Wansink DG, et al. (2000). "The zyxin-related protein TRIP6 interacts with PDZ motifs in the adaptor protein RIL and the protein tyrosine phosphatase PTP-BL". Eur. J. Cell Biol. 79 (4): 283–93. doi:10.1078/S0171-9335(04)70031-X. PMID10826496.
Walma T, Spronk CA, Tessari M, et al. (2002). "Structure, dynamics and binding characteristics of the second PDZ domain of PTP-BL". J. Mol. Biol. 316 (5): 1101–10. doi:10.1006/jmbi.2002.5402. PMID11884147.
Omasu F, Ezura Y, Kajita M, et al. (2003). "Association of genetic variation of the RIL gene, encoding a PDZ-LIM domain protein and localized in 5q31.1, with low bone mineral density in adult Japanese women". J. Hum. Genet. 48 (7): 342–5. doi:10.1007/s10038-003-0035-1. PMID12908099.
Vallenius T, Scharm B, Vesikansa A, et al. (2004). "The PDZ-LIM protein RIL modulates actin stress fiber turnover and enhances the association of alpha-actinin with F-actin". Exp. Cell Res. 293 (1): 117–28. doi:10.1016/j.yexcr.2003.09.004. PMID14729062.
van den Berk LC, van Ham MA, te Lindert MM, et al. (2005). "The interaction of PTP-BL PDZ domains with RIL: an enigmatic role for the RIL LIM domain". Mol. Biol. Rep. 31 (4): 203–15. doi:10.1007/s11033-005-1407-8. PMID15663004.
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID16189514.
Boumber YA, Kondo Y, Chen X, et al. (2007). "RIL, a LIM gene on 5q31, is silenced by methylation in cancer and sensitizes cancer cells to apoptosis". Cancer Res. 67 (5): 1997–2005. doi:10.1158/0008-5472.CAN-06-3093. PMID17332327.