PLASMIC score for estimating the risk of ADAMPTS13 deficiency

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Saeedeh Kowsarnia M.D.[2]

Overview

PLASMIC score

Platelet count (< 30,000/microL)
Hemolysis variables (Retic count > 2.5%, undetectable haptoglobin, indirect billi <2 mg/dL( >34 mcmol/L))
Absence of active cancer
Absence of transplant history (solid, stem cell)
MCV < 90 Fl
INR < 1.5
Serum creatinine < 2 mg/dL (<177 mcmol/L)
Score:

Risk of ADAMPTS13 deficiency in adults with suspected TTP [1]:

  • Low-risk = 0 to 4 points
  • Intermediate risk = 5 points
  • High-risk = 6 to 7 points

References

  1. ↑ Jamme, Matthieu; Rondeau, Eric (2017). "The PLASMIC score for thrombotic thrombocytopenic purpura". The Lancet Haematology. 4 (4): e148–e149. doi:10.1016/S2352-3026(17)30024-8. ISSN 2352-3026.
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