PNPLA6
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Patatin-like phospholipase domain containing 6 | |||||||
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Identifiers | |||||||
Symbols | PNPLA6 ; NTE; sws | ||||||
External IDs | Template:OMIM5 Template:MGI HomoloGene: 21333 | ||||||
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RNA expression pattern | |||||||
File:PBB GE PNPLA6 203718 at tn.png | |||||||
More reference expression data | |||||||
Orthologs | |||||||
Template:GNF Ortholog box | |||||||
Species | Human | Mouse | |||||
Entrez | n/a | n/a | |||||
Ensembl | n/a | n/a | |||||
UniProt | n/a | n/a | |||||
RefSeq (mRNA) | n/a | n/a | |||||
RefSeq (protein) | n/a | n/a | |||||
Location (UCSC) | n/a | n/a | |||||
PubMed search | n/a | n/a |
Patatin-like phospholipase domain containing 6, also known as PNPLA6, is a human gene.[1]
References
Further reading
- Glynn P (2000). "Neural development and neurodegeneration: two faces of neuropathy target esterase". Prog. Neurobiol. 61 (1): 61–74. PMID 10759065.
- Maroni M, Bleecker ML (1986). "Neuropathy target esterase in human lymphocytes and platelets". Journal of applied toxicology : JAT. 6 (1): 1–7. PMID 3958422.
- Bertoncin D, Russolo A, Caroldi S, Lotti M (1985). "Neuropathy target esterase in human lymphocytes". Arch. Environ. Health. 40 (3): 139–44. PMID 4026382.
- Gurba PE, Richardson RJ (1983). "Partial characterization of neurotoxic esterase of human placenta". Toxicol. Lett. 15 (1): 13–7. PMID 6836585.
- Lush MJ, Li Y, Read DJ; et al. (1998). "Neuropathy target esterase and a homologous Drosophila neurodegeneration-associated mutant protein contain a novel domain conserved from bacteria to man". Biochem. J. 332 ( Pt 1): 1–4. PMID 9576844.
- van Tienhoven M, Atkins J, Li Y, Glynn P (2002). "Human neuropathy target esterase catalyzes hydrolysis of membrane lipids". J. Biol. Chem. 277 (23): 20942–8. doi:10.1074/jbc.M200330200. PMID 11927584.
- Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
- Li Y, Dinsdale D, Glynn P (2003). "Protein domains, catalytic activity, and subcellular distribution of neuropathy target esterase in Mammalian cells". J. Biol. Chem. 278 (10): 8820–5. doi:10.1074/jbc.M210743200. PMID 12514188.
- Winrow CJ, Hemming ML, Allen DM; et al. (2003). "Loss of neuropathy target esterase in mice links organophosphate exposure to hyperactivity". Nat. Genet. 33 (4): 477–85. doi:10.1038/ng1131. PMID 12640454.
- Zaccheo O, Dinsdale D, Meacock PA, Glynn P (2004). "Neuropathy target esterase and its yeast homologue degrade phosphatidylcholine to glycerophosphocholine in living cells". J. Biol. Chem. 279 (23): 24024–33. doi:10.1074/jbc.M400830200. PMID 15044461.
- Beausoleil SA, Jedrychowski M, Schwartz D; et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. doi:10.1073/pnas.0404720101. PMID 15302935.
- Chang PA, Wu YJ, Chen R; et al. (2005). "Inhibition of neuropathy target esterase expressing by antisense RNA does not affect neural differentiation in human neuroblastoma (SK-N-SH) cell line". Mol. Cell. Biochem. 272 (1–2): 47–54. PMID 16010971.
- Chang PA, Chen R, Wu YJ (2006). "Reduction of neuropathy target esterase does not affect neuronal differentiation, but moderate expression induces neuronal differentiation in human neuroblastoma (SK-N-SH) cell line". Brain Res. Mol. Brain Res. 141 (1): 30–8. doi:10.1016/j.molbrainres.2005.07.012. PMID 16122834.
- Kimura K, Wakamatsu A, Suzuki Y; et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMID 16344560.
- Wilson PA, Gardner SD, Lambie NM; et al. (2006). "Characterization of the human patatin-like phospholipase family". J. Lipid Res. 47 (9): 1940–9. doi:10.1194/jlr.M600185-JLR200. PMID 16799181.
- Chang PA, Liu ChY, Chen R, Wu YJ (2006). "Effect of over-expression of neuropathy target esterase on mammalian cell proliferation". Cell Prolif. 39 (5): 429–40. doi:10.1111/j.1365-2184.2006.00399.x. PMID 16987144.
- Chen R, Chang PA, Long DX; et al. (2007). "Down-regulation of neuropathy target esterase by protein kinase C activation with PMA stimulation". Mol. Cell. Biochem. 302 (1–2): 179–85. doi:10.1007/s11010-007-9439-0. PMID 17385009.
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