POSTN

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Periostin, osteoblast specific factor
Identifiers
Symbols POSTN ; MGC119510; MGC119511; OSF-2; PDLPOSTN; PN; RP11-412K4.1; periostin
External IDs Template:OMIM5 Template:MGI HomoloGene4730
RNA expression pattern
File:PBB GE POSTN 210809 s at tn.png
More reference expression data
Orthologs
Template:GNF Ortholog box
Species Human Mouse
Entrez n/a n/a
Ensembl n/a n/a
UniProt n/a n/a
RefSeq (mRNA) n/a n/a
RefSeq (protein) n/a n/a
Location (UCSC) n/a n/a
PubMed search n/a n/a

Periostin, osteoblast specific factor, also known as POSTN, is a human gene.[1]


References

  1. "Entrez Gene: POSTN periostin, osteoblast specific factor".

Further reading

  • Takeshita S, Kikuno R, Tezuka K, Amann E (1993). "Osteoblast-specific factor 2: cloning of a putative bone adhesion protein with homology with the insect protein fasciclin I.". Biochem. J. 294 ( Pt 1): 271–8. PMID 8363580.
  • Sasaki H, Dai M, Auclair D; et al. (2001). "Serum level of the periostin, a homologue of an insect cell adhesion molecule, as a prognostic marker in nonsmall cell lung carcinomas". Cancer. 92 (4): 843–8. PMID 11550156.
  • Gillan L, Matei D, Fishman DA; et al. (2002). "Periostin secreted by epithelial ovarian carcinoma is a ligand for alpha(V)beta(3) and alpha(V)beta(5) integrins and promotes cell motility". Cancer Res. 62 (18): 5358–64. PMID 12235007.
  • Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
  • Ota T, Suzuki Y, Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Dunham A, Matthews LH, Burton J; et al. (2004). "The DNA sequence and analysis of human chromosome 13". Nature. 428 (6982): 522–8. doi:10.1038/nature02379. PMID 15057823.
  • Shao R, Bao S, Bai X; et al. (2004). "Acquired expression of periostin by human breast cancers promotes tumor angiogenesis through up-regulation of vascular endothelial growth factor receptor 2 expression". Mol. Cell. Biol. 24 (9): 3992–4003. PMID 15082792.
  • Bao S, Ouyang G, Bai X; et al. (2004). "Periostin potently promotes metastatic growth of colon cancer by augmenting cell survival via the Akt/PKB pathway". Cancer Cell. 5 (4): 329–39. PMID 15093540.
  • Kim CJ, Yoshioka N, Tambe Y; et al. (2005). "Periostin is down-regulated in high grade human bladder cancers and suppresses in vitro cell invasiveness and in vivo metastasis of cancer cells". Int. J. Cancer. 117 (1): 51–8. doi:10.1002/ijc.21120. PMID 15880581.
  • Chang Y, Lee TC, Li JC; et al. (2005). "Differential expression of osteoblast-specific factor 2 and polymeric immunoglobulin receptor genes in nasopharyngeal carcinoma". Head Neck. 27 (10): 873–82. doi:10.1002/hed.20253. PMID 16136586.
  • Liu T, Qian WJ, Gritsenko MA; et al. (2006). "Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry". J. Proteome Res. 4 (6): 2070–80. doi:10.1021/pr0502065. PMID 16335952.
  • Yan W, Shao R (2006). "Transduction of a mesenchyme-specific gene periostin into 293T cells induces cell invasive activity through epithelial-mesenchymal transformation". J. Biol. Chem. 281 (28): 19700–8. doi:10.1074/jbc.M601856200. PMID 16702213.
  • Försti A, Jin Q, Altieri A; et al. (2007). "Polymorphisms in the KDR and POSTN genes: association with breast cancer susceptibility and prognosis". Breast Cancer Res. Treat. 101 (1): 83–93. doi:10.1007/s10549-006-9265-1. PMID 16807673.
  • Grigoriadis A, Mackay A, Reis-Filho JS; et al. (2007). "Establishment of the epithelial-specific transcriptome of normal and malignant human breast cells based on MPSS and array expression data". Breast Cancer Res. 8 (5): R56. doi:10.1186/bcr1604. PMID 17014703.
  • Baril P, Gangeswaran R, Mahon PC; et al. (2007). "Periostin promotes invasiveness and resistance of pancreatic cancer cells to hypoxia-induced cell death: role of the beta4 integrin and the PI3k pathway". Oncogene. 26 (14): 2082–94. doi:10.1038/sj.onc.1210009. PMID 17043657.
  • Siriwardena BS, Kudo Y, Ogawa I; et al. (2007). "Periostin is frequently overexpressed and enhances invasion and angiogenesis in oral cancer". Br. J. Cancer. 95 (10): 1396–403. doi:10.1038/sj.bjc.6603431. PMID 17060937.
  • Li JS, Sun GW, Wei XY, Tang WH (2007). "Expression of periostin and its clinicopathological relevance in gastric cancer". World J. Gastroenterol. 13 (39): 5261–6. PMID 17876898.

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