Pancreatic fistula history and symptoms

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

Overview

A pancreatic fistula with leakage of fluid can be diagnosed in some cases with typical history and clinical presentation, such as patient presenting with pancreatitis followed by recurrence, persistent symptoms or post pancreatic resection fluid drainage with increase amylase level. Patients diagnosed with pancreatic fistula are sometimes asymptomatic while some patients may present with symptoms such as marked recent weight loss, unresponsiveness of the ascites to diuretics, non-specific symptoms such as nausea, vomiting, hypotension, infection, and tachycardia and some patients with a high grade fistula may present with sepsis

History and Symptoms

History

  • A pancreatic fistula with leakage of fluid can be diagnosed in some cases with typical history and clinical presentation, such as patient presenting with pancreatitis followed by recurrence, persistent symptoms or post pancreatic resection fluid drainage with increase amylase level.[1][2]
  • However, most cases are far more challenging which require imaging techniques and examination of the fluid samples withdrawn from the leak to help diagnose the fistula.[3]

Symptoms

Patients diagnosed with pancreatic fistula are sometimes asymptomatic while some patients may have the following symptoms:[3]

References

  1. "StatPearls". 2021. PMID 32809706 Check |pmid= value (help).
  2. Johnston, M. J.; Prew, C. L.; Fraser, I. (2013). "An unusual case of pancreatic fistula". Journal of Surgical Case Reports. 2013 (3): rjt014–rjt014. doi:10.1093/jscr/rjt014. ISSN 2042-8812.
  3. 3.0 3.1 Larsen M, Kozarek R (2014). "Management of pancreatic ductal leaks and fistulae". J Gastroenterol Hepatol. 29 (7): 1360–70. doi:10.1111/jgh.12574. PMID 24650171.

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