Parathyroid cancer medical therapy

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ammu Susheela, M.D. [2]

Overview

The predominant therapy for parathyroid cancer is surgical resection. Adjunctive supportive therapy, chemotherapy, and radiation may be required. Supportive therapy for parathyroid cancer includes IV fluids, diuretics, and calcimimetic agents.

Medical Therapy

• There are different types of treatment for patients with parathyroid cancer.
• Treatment includes the control of hypercalcemia among patients who have an overactive parathyroid gland.

Standard Therapy

• Four types of standard treatment are used:

• Surgery
• Radiation therapy
• Chemotherapy
• Supportive care
• Follow-up tests may be needed

Supportive Care

• Supportive care is given to lessen the problems caused by the disease or its treatment. Supportive care for hypercalcemia caused by parathyroid cancer may include the following:

• Intravenous (IV) fluids
• Diuretics
• Antiresorptive agents such as biphosphonates, gallium, or mithramycin

• Calcimimetic agents that directly block secretion of the parathyroid hormone from the glands

• Gallium nitrate to reduce the calcium levels
• Calcitonin to control the calcium levels

References

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