Pernicious anemia natural history, complications and prognosis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Natural History

Complications

  • People with pernicious anemia may have gastric polyps, and they are at increased risk for gastric cancer and gastric carcinoid tumors.
  • Brain and nervous system (neurological) problems may continue if treatment is delayed.

Prognosis

  • The outcome is usually excellent with treatment.
  • Any damage to nerves may be permanent, especially if treatment is not started within 6 months of when symptoms began.

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