Phenazopyridine (patient information)

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Why is this medication prescribed

Phenazopyridine relieves urinary tract pain, burning, irritation, and discomfort, as well as urgent and frequent urination caused by urinary tract infections, surgery, injury, or examination procedures. However, phenazopyridine is not an antibiotic; it does not cure infections.

This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.

How should this medicine be used

Phenazopyridine comes as a tablet to take by mouth. It usually is taken three times a day after meals. Do not chew or crush the tablets; swallow them whole with a full glass of water. You may stop taking this drug when pain and discomfort completely disappear. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take phenazopyridine exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

What special precautions should I follow

Before taking phenazopyridine:

  • tell your doctor and pharmacist if you are allergic to phenazopyridine or any other drugs.
  • tell your doctor and pharmacist what prescription and nonprescription medications you are taking, including vitamins.
  • tell your doctor if you have or have ever had kidney disease or glucose-6-phosphate dehydrogenase (G-6-PD) deficiency (an inherited blood disease).
  • tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking phenazopyridine, call your doctor.

What should I do if I forget a dose

Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

Side effects

Mild side effects

Phenazopyridine may cause side effects. Your urine may turn a red-orange or brown; this effect is harmless. Tell your doctor if any of these symptoms are severe or do not go away:

  • headache
  • dizziness
  • upset stomach

Severe side effects

If you experience any of the following symptoms, call your doctor immediately:

  • yellowing of the skin or eyes
  • fever
  • confusion
  • skin discoloration (blue to bluish-purple)
  • shortness of breath
  • skin rash
  • sudden decrease in the amount of urine
  • swelling of the face, fingers, feet, or legs

If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online [at http://www.fda.gov/MedWatch/report.htm] or by phone [1-800-332-1088].

What storage conditions are needed for this medicine

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.

In case of emergency/overdose

In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.

What other information should I know

Keep all appointments with your doctor and the laboratory. Your doctor will order certain lab tests to check your response to phenazopyridine.

Phenazopyridine can interfere with laboratory tests, including urine tests for glucose (sugar) and ketones. If you have diabetes, you should use Clinitest rather than Tes-Tape or Clinistix to test your urine for sugar. Urine tests for ketones (Acetest and Ketostix) may give false results. Before you have any tests, tell the laboratory personnel and doctor that you take this medication.

Phenazopyridine stains clothing and contact lenses. Avoid wearing contact lenses while taking this medicine.

Do not let anyone else take your medication. Your prescription is probably not refillable.

If you still have symptoms after you finish the phenazopyridine, call your doctor.

Brand names

  • Azo-Dine®
  • Azo-Gesic®
  • Azo-Natural®
  • Azo-Standard®
  • Baridium®
  • Prodium®
  • Pyridium®
  • Re-Azo®
  • UTI Relief®

Brand names of combination products

  • Pyridium® Plus containing Phenazopyridine Hydrochloride, Butabarbital, and Hyoscyamine Hydrobromide