Pneumoconiosis other diagnostic studies

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Dushka Riaz, MD

Overview

Pulmonary function tests, bronchoscopy, and lung biopsies may be helpful in the diagnosis of pneumoconiosis.

Other diagnostic studies for pneumoconiosis include: ^[1] ^[2] ^[3] ^[4] ^[5]

Pulmonary function tests (PFT), which demonstrates:
- Decreased FEV1 and FEV1/FVC ratio
- Decreased DLCO
- Decreased compliance
Bronchoalveolar lavage:
- Can be used to study cytology and exclude other pathologies
- Asbestos bodies can be identified to diagnose asbestosis
- Can be used to diagnose berylliosis with a beryllium lymphocyte proliferation test
Lung biopsy can be used to confirm the pneumoconiosis
- Noncaseating granulomas can be seen in berylliosis

↑ Wang XR, Christiani DC (2000). "Respiratory symptoms and functional status in workers exposed to silica, asbestos, and coal mine dusts". J Occup Environ Med. 42 (11): 1076–84. doi:10.1097/00043764-200011000-00009. PMID 11094786.
↑ Bégin R, Ostiguy G, Cantin A, Bergeron D (1988). "Lung function in silica-exposed workers. A relationship to disease severity assessed by CT scan". Chest. 94 (3): 539–45. doi:10.1378/chest.94.3.539. PMID 3409733.
↑ "American Thoracic Society. Medical Section of the American Lung Association: The diagnosis of nonmalignant diseases related to asbestos". Am Rev Respir Dis. 134 (2): 363–8. 1986. doi:10.1164/arrd.1986.134.2.363. PMID 3740660.
↑ De Vuyst P, Jedwab J, Dumortier P, Vandermoten G, Vande Weyer R, Yernault JC (1982). "Asbestos bodies in bronchoalveolar lavage". Am Rev Respir Dis. 126 (6): 972–6. doi:10.1164/arrd.1982.126.6.972. PMID 7181238.
↑ Balmes JR, Abraham JL, Dweik RA, Fireman E, Fontenot AP, Maier LA; et al. (2014). "An official American Thoracic Society statement: diagnosis and management of beryllium sensitivity and chronic beryllium disease". Am J Respir Crit Care Med. 190 (10): e34–59. doi:10.1164/rccm.201409-1722ST. PMID 25398119.