Polyarthritis with joint swelling, fever, and weight loss
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Eiman Ghaffarpasand, M.D. [2]
Diseases | Clinical manifestations | Para-clinical findings | Gold standard | Additional findings | |||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Symptoms | Physical examination | ||||||||||||||||||
Lab Findings | Imaging | Histopathology | |||||||||||||||||
Joint Swelling | Fever | Weight loss | Claudication | Morning stiffness | Local erythema | Skin manifestation | CBC | ESR | Synovial fluid | Other | X-ray | CT scan | Other | ||||||
Polyarthritis | Infectious arthritis | Lyme disease[1] | + | + | +/- | +/- | - | - | Erythema migrans | Leukopenia, Thrombocytopenia | - | Cell counts 500-98,000/µL | Microscopic hematuria, Proteinuria, ↑ALT or AST | - | - | - | Fibrosis of the deeper dermis and hyalinization of collagen bundles | Serologic tests | Erythema migrans |
Bacterial endocarditis[2] | + | + | + | - | - | +/- | Janeway lesions, Osler nodes, Roth spots | Normochromic-normocytic anemia | ↑ | ↑WBC, S. aureus in culture | Hyperglobulinemia, Cryoglobulinemia | Joint erosion and effusion | - | - | Vegetation or intracardiac abscess demonstrating active endocarditis | Echocardiography (TTE) | Vertebral osteomyelitis | ||
Polyarticular pain | Viral arthritis | Parvovirus[3] | + | + | +/- | - | - | - | Fifth disease/ Erythema infectiosum | Aplastic crisis | ↑ | Normal | ANA, RF, CRP | Joint swelling | - | - | Immune complex deposition | Parvovirus IgM antibody | Transient aplastic crisis, Fetal infection |
References
- ↑ Lantos PM (2015). "Chronic Lyme disease". Infect Dis Clin North Am. 29 (2): 325–40. doi:10.1016/j.idc.2015.02.006. PMC 4477530. PMID 25999227.
- ↑ Soor P, Sharma N, Rao C (2017). "Multifocal Septic Arthritis Secondary to Infective Endocarditis: A Rare Case Report". J Orthop Case Rep. 7 (1): 65–68. doi:10.13107/jocr.2250-0685.692. PMC 5458702. PMID 28630844.
- ↑ Moore TL (July 2000). "Parvovirus-associated arthritis". Curr Opin Rheumatol. 12 (4): 289–94. PMID 10910181.