Pou class 3 homeobox 3

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Identifiers
Aliases
External IDs	GeneCards: [1]
Orthologs
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a
Wikidata
View/Edit Human

POU class 3 homeobox 3 is a protein that in humans is encoded by the POU3F3 gene.

Function

This gene encodes a POU-domain containing protein that functions as a transcription factor. The encoded protein recognizes an octamer sequence in the DNA of target genes. This protein may play a role in development of the nervous system. [provided by RefSeq, Apr 2015].

Further reading

• Li W, Zheng J, Deng J, You Y, Wu H, Li N, Lu J, Zhou Y (June 2014). "Increased levels of the long intergenic non-protein coding RNA POU3F3 promote DNA methylation in esophageal squamous cell carcinoma cells". Gastroenterology. 146 (7): 1714–26.e5. doi:10.1053/j.gastro.2014.03.002. PMID 24631494.
• Guo H, Wu L, Yang Q, Ye M, Zhu X (January 2015). "Functional linc-POU3F3 is overexpressed and contributes to tumorigenesis in glioma". Gene. 554 (1): 114–9. doi:10.1016/j.gene.2014.10.038. PMID 25445282.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.