Precursor mRNA

Please Take Over This Page and Apply to be Editor-In-Chief for this topic: There can be one or more than one Editor-In-Chief. You may also apply to be an Associate Editor-In-Chief of one of the subtopics below. Please mail us [1] to indicate your interest in serving either as an Editor-In-Chief of the entire topic or as an Associate Editor-In-Chief for a subtopic. Please be sure to attach your CV and or biographical sketch.

WikiDoc Resources for Precursor mRNA
Articles
Most recent articles on Precursor mRNA Most cited articles on Precursor mRNA Review articles on Precursor mRNA Articles on Precursor mRNA in N Eng J Med, Lancet, BMJ
Media
Powerpoint slides on Precursor mRNA Images of Precursor mRNA Photos of Precursor mRNA Podcasts & MP3s on Precursor mRNA Videos on Precursor mRNA
Evidence Based Medicine
Cochrane Collaboration on Precursor mRNA Bandolier on Precursor mRNA TRIP on Precursor mRNA
Clinical Trials
Ongoing Trials on Precursor mRNA at Clinical Trials.gov Trial results on Precursor mRNA Clinical Trials on Precursor mRNA at Google
Guidelines / Policies / Govt
US National Guidelines Clearinghouse on Precursor mRNA NICE Guidance on Precursor mRNA NHS PRODIGY Guidance FDA on Precursor mRNA CDC on Precursor mRNA
Books
Books on Precursor mRNA
News
Precursor mRNA in the news Be alerted to news on Precursor mRNA News trends on Precursor mRNA
Commentary
Blogs on Precursor mRNA
Definitions
Definitions of Precursor mRNA
Patient Resources / Community
Patient resources on Precursor mRNA Discussion groups on Precursor mRNA Patient Handouts on Precursor mRNA Directions to Hospitals Treating Precursor mRNA Risk calculators and risk factors for Precursor mRNA
Healthcare Provider Resources
Symptoms of Precursor mRNA Causes & Risk Factors for Precursor mRNA Diagnostic studies for Precursor mRNA Treatment of Precursor mRNA
Continuing Medical Education (CME)
CME Programs on Precursor mRNA
International
Precursor mRNA en Espanol Precursor mRNA en Francais
Business
Precursor mRNA in the Marketplace Patents on Precursor mRNA
Experimental / Informatics
List of terms related to Precursor mRNA

Overview

Precursor mRNA, more correctly termed heterogeneous nuclear RNA (hnRNA), is an immature single strand of messenger ribonucleic acid (mRNA). HnRNA is synthesized from a DNA template in the cell nucleus by a process called transcription.

Once hnRNA has been completely processed, it is termed "mature messenger RNA", "mature mRNA", or simply "mRNA".

Processing

Eukaryotic hnRNA exists only briefly before it is fully processed into mRNA. HnRNAs include two different types of segments, exons and introns. Exons are segments that are retained in the final mRNA, while introns are removed in a process called splicing, which is performed by the spliceosome.

Additional processing steps attach modifications to the 5' and 3' ends of the hnRNA. These include a 5' cap of 7-methylguanosine and a poly-A tail.

When an hnRNA strand has been properly processed, becoming an mRNA sequence, it is exported out of the nucleus and eventually translated into a protein... a process accomplished in conjunction with ribosomes.

External links

• Scienceden.com RNA Article