Primary amyloidosis echocardiography and ultrasound
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Shaghayegh Habibi, M.D.[2] Shyam Patel [3]
Overview
Echocardiography is critical in the diagnosis of cardiac involvement in primary amyloidosis. Echocardiogram should be done at diagnosis and routinely thereafter to monitor response to therapy.
Echocardiography/Ultrasound
- Findings on echocardiography suggestive of cardiac involvement in primary amyloidosis include:[1][2][3]
- Sparkling or speckled appearance of the left ventricular thickening
- Hypertrophied right ventricle
- Diastolic dysfunction with restrictive filling pattern (in the advanced stages)
- Severe atrial dilatation
- Thickening of the interatrial septum
- Pericardial effusion
- Prominent valves
References
- ↑ Klein AL, Hatle LK, Burstow DJ, Seward JB, Kyle RA, Bailey KR, Luscher TF, Gertz MA, Tajik AJ (April 1989). "Doppler characterization of left ventricular diastolic function in cardiac amyloidosis". J. Am. Coll. Cardiol. 13 (5): 1017–26. PMID 2647814.
- ↑ Pantazis A, Vischer AS, Perez-Tome MC, Castelletti S (March 2015). "Diagnosis and management of hypertrophic cardiomyopathy". Echo Res Pract. 2 (1): R45–53. doi:10.1530/ERP-15-0007. PMC 4676455. PMID 26693331.
- ↑ Eshaghian S, Kaul S, Shah PK (2007). "Cardiac amyloidosis: new insights into diagnosis and management". Rev Cardiovasc Med. 8 (4): 189–99. PMID 18192942.