Prolactinoma history and symptoms

Prolactinoma Microchapters
Home
Patient Information
Overview
Historical Perspective
Classification
Pathophysiology
Causes
Differentiating Prolactinoma from other Diseases
Epidemiology and Demographics
Risk Factors
Screening
Natural History, Complications and Prognosis
Diagnosis
History and Symptoms
Physical Examination
Laboratory Findings
ECG
X-ray
Ultrasound
CT
MRI
Other Imaging Findings
Other Diagnostic Studies
Treatment
Medical Therapy
Surgery
Primary Prevention
Secondary Prevention
Cost-Effectiveness of Therapy
Future or Investigational Therapies
Case Studies
Case #1
Prolactinoma history and symptoms On the Web
Most recent articles
Most cited articles
Review articles
CME Programs
Powerpoint slides
Images
American Roentgen Ray Society Images of Prolactinoma history and symptoms All Images X-rays Echo & Ultrasound CT Images MRI
Ongoing Trials at Clinical Trials.gov
US National Guidelines Clearinghouse
NICE Guidance
FDA on Prolactinoma history and symptoms
CDC on Prolactinoma history and symptoms
Prolactinoma history and symptoms in the news
Blogs on Prolactinoma history and symptoms
Directions to Hospitals Treating Prolactinoma
Risk calculators and risk factors for Prolactinoma history and symptoms

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Anmol Pitliya, M.B.B.S. M.D.[2],Faizan Sheraz, M.D. [3]

Overview

Common symptoms of prolactinoma include headache, vision changes, decreased libido, infertility, and osteoporosis. In women, common symptoms of prolactinoma include breast tenderness, galactorrhea, and amenorrhea or oligomenorrhea.

History

Obtaining the history is one of the most important aspects of making a diagnosis of prolactinoma. A complete history will help determine the correct therapy and helps in determining the prognosis.

Past medical history

• Specific areas of focus when obtaining the past medical history are outlined below:
  • Headache
  • Vision changes and visual field defects
  • Delayed puberty in adolescence
  • Decreased sexual drive (libido)
  • Infrequent menstrual period or absent menstrual period
  • Breast tenderness
  • Abnormal milk flow from the breast in a woman who is not pregnant or nursing

Family history

• Family history of multiple endocrine neoplasia type 1 (MEN1) is assosciated with a higher chance of developing pitutary adenomas (prolactinomas being the most common type of pitutary adenomas).

Symptoms

Symptoms of prolactinoma can be divided as follows:

• Symptoms due to hyperprolactinemia
• Symptoms due to mass effect

Symptoms of Prolactinoma
Symptoms due to hyperprolactinemia			Symptoms due to mass effect
Women	Men	Both men and women	Both men and women
Amenorrhea/oligomenorrhea Galactorrhea Breast tenderness	Impotence	Infertility Decreased libido Osteoporosis	Common Symptoms: Headache Vision changes Temporal field defects (bitemporal hemianopsia) Less Common Symptoms: Cranial nerve palsies Hypothalamic impairment Hydrocephalus Hypopituitarism Cerebrospinal fluid rhinorrhea

References

Template:WikiDoc Sources ​