Q fever natural history, complications, and prognosis
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Ahmed Younes M.B.B.CH [2]
Overview
Acute Q fever has a good prognosis even without treatment. Chronic Q fever has a less favorable prognosis.
Natural history
Acute Q fever
If left untreated, most patients will recover within several months.[1]
Chronic Q fever
If left untreated, chronic Q fever is usually deadly. However, with appropriate treatment, the case fatality rate is around 10%.[1]
Complications
Pulmonary
- Atypical pneumonia
- Acute respiratory distress syndrome (ARDS) in rare cases
Cardiac
Hepatic
Musculoskeletal
Obstetric
Prognosis
Acute Q fever
- Acute Q fever is responsive to treatment and even without treatment, mortality rate is 1-2%.
Chronic Q fever
- Chronic Q fever is more serious, with a case fatality rate of 10% after treatment.[2]
References
- ↑ 1.0 1.1 Ishikawa H, Maeda H, Takamatsu H, Saito Y (1979). "Systemic hyalinosis (juvenile hyaline fibromatosis). Ultrastructure of the hyaline with particular reference to the cross-banded structure". Arch. Dermatol. Res. 265 (2): 195–206. PMID 88923.
- ↑ Hartzell JD, Wood-Morris RN, Martinez LJ, Trotta RF (2008). "Q fever: epidemiology, diagnosis, and treatment". Mayo Clin. Proc. 83 (5): 574–9. doi:10.4065/83.5.574. PMID 18452690.