Regenerating islet-derived protein 4 is a protein that in humans is encoded by the REG4gene.[1][2][3]
References
↑Hartupee JC, Zhang H, Bonaldo MF, Soares MB, Dieckgraefe BK (Apr 2001). "Isolation and characterization of a cDNA encoding a novel member of the human regenerating protein family: Reg IV". Biochim Biophys Acta. 1518 (3): 287–93. doi:10.1016/s0167-4781(00)00284-0. PMID11311942.
↑Violette S, Festor E, Pandrea-Vasile I, Mitchell V, Adida C, Dussaulx E, Lacorte JM, Chambaz J, Lacasa M, Lesuffleur T (Nov 2002). "Reg IV, a new member of the regenerating gene family, is overexpressed in colorectal carcinomas". Int J Cancer. 103 (2): 185–93. doi:10.1002/ijc.10788. PMID12455032.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID14702039.
Gu Z, Rubin MA, Yang Y, et al. (2005). "Reg IV: a promising marker of hormone refractory metastatic prostate cancer". Clin. Cancer Res. 11 (6): 2237–43. doi:10.1158/1078-0432.CCR-04-0356. PMID15788672.
Bishnupuri KS, Luo Q, Murmu N, et al. (2006). "Reg IV activates the epidermal growth factor receptor/Akt/AP-1 signaling pathway in colon adenocarcinomas". Gastroenterology. 130 (1): 137–49. doi:10.1053/j.gastro.2005.10.001. PMID16401477.
Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. doi:10.1038/nature04727. PMID16710414.
Takehara A, Eguchi H, Ohigashi H, et al. (2006). "Novel tumor marker REG4 detected in serum of patients with resectable pancreatic cancer and feasibility for antibody therapy targeting REG4". Cancer Sci. 97 (11): 1191–7. doi:10.1111/j.1349-7006.2006.00297.x. PMID16918991.