RPL29

Ribosomal protein L29
Identifiers
Symbols	RPL29 ; HIP; HUMRPL29; MGC88589
External IDs	Template:OMIM5 Template:MGI HomoloGene: 87621
Gene ontology Molecular function Template:GNF GO Template:GNF GO Template:GNF GO Cellular component Template:GNF GO Template:GNF GO Template:GNF GO Biological process Template:GNF GO Template:GNF GO
RNA expression pattern
File:PBB GE RPL29 200823 x at tn.png
File:PBB GE RPL29 213969 x at tn.png
File:PBB GE RPL29 gnf1h06909 s at tn.png
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Ribosomal protein L29, also known as RPL29, is a human gene.

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a cytoplasmic ribosomal protein that is a component of the 60S subunit. The protein belongs to the L29E family of ribosomal proteins. The protein is also a peripheral membrane protein expressed on the cell surface that directly binds heparin. Although this gene was previously reported to map to 3q29-qter, it is believed that it is located at 3p21.3-p21.2. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.

Further reading

• Wool IG, Chan YL, Glück A (1996). "Structure and evolution of mammalian ribosomal proteins". Biochem. Cell Biol. 73 (11–12): 933–47. PMID 8722009.CS1 maint: Multiple names: authors list (link)
• Nika H, Hultin T (1984). "Location of the sulfhydryl groups involved in disulfide interaction between the neighboring proteins L6 and L29 in mammalian ribosomes. S-cleavage of the cyanylated proteins in polyacrylamide gels after separation by dodecylsulfate gel electrophoresis". Eur. J. Biochem. 142 (3): 521–6. PMID 6468376.
• Law PT, Tsui SK, Lam WY; et al. (1996). "A novel cDNA encoding a human homologue of ribosomal protein L29". Biochim. Biophys. Acta. 1305 (3): 105–8. PMID 8597591.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Liu S, Smith SE, Julian J; et al. (1996). "cDNA cloning and expression of HIP, a novel cell surface heparan sulfate/heparin-binding protein of human uterine epithelial cells and cell lines". J. Biol. Chem. 271 (20): 11817–23. PMID 8662616.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Rohde LH, Julian J, Babaknia A, Carson DD (1996). "Cell surface expression of HIP, a novel heparin/heparan sulfate binding protein, of human uterine epithelial cells and cell lines". J. Biol. Chem. 271 (20): 11824–30. PMID 8662617.CS1 maint: Multiple names: authors list (link)
• Jacobs AL, Julian J, Sahin AA, Carson DD (1997). "Heparin/heparan sulfate interacting protein expression and functions in human breast cancer cells and normal breast epithelia". Cancer Res. 57 (22): 5148–54. PMID 9371517.CS1 maint: Multiple names: authors list (link)
• Garcia-Barcelo M, Law PT, Tsui SK; et al. (1998). "Mapping of the human ribosomal large subunit protein gene RPL29 to human chromosome 3q29-qter". Genomics. 46 (1): 148–51. doi:10.1006/geno.1997.4990. PMID 9403071.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Koldamova RP, Lefterov IM, DiSabella MT; et al. (1999). "Human bleomycin hydrolase binds ribosomal proteins". Biochemistry. 38 (22): 7111–7. doi:10.1021/bi990135l. PMID 10353821.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Kudo H, Senju S, Mitsuya H, Nishimura Y (2000). "Mouse and human GTPBP2, newly identified members of the GP-1 family of GTPase". Biochem. Biophys. Res. Commun. 272 (2): 456–65. doi:10.1006/bbrc.2000.2763. PMID 10833435.CS1 maint: Multiple names: authors list (link)
• Uechi T, Tanaka T, Kenmochi N (2001). "A complete map of the human ribosomal protein genes: assignment of 80 genes to the cytogenetic map and implications for human disorders". Genomics. 72 (3): 223–30. doi:10.1006/geno.2000.6470. PMID 11401437.CS1 maint: Multiple names: authors list (link)
• Kirn-Safran CB, Julian J, Fongemie JE; et al. (2002). "Changes in the cytologic distribution of heparin/heparan sulfate interacting protein/ribosomal protein L29 (HIP/RPL29) during in vivo and in vitro mouse mammary epithelial cell expression and differentiation". Dev. Dyn. 223 (1): 70–84. doi:10.1002/dvdy.1226. PMID 11803571.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Hoke DE, Carson DD, Höök M (2006). "A heparin binding synthetic peptide from human HIP / RPL29 fails to specifically differentiate between anticoagulantly active and inactive species of heparin". Journal of negative results in biomedicine. 2: 1. PMID 12659638.CS1 maint: Multiple names: authors list (link)
• Odintsova TI, Müller EC, Ivanov AV; et al. (2004). "Characterization and analysis of posttranslational modifications of the human large cytoplasmic ribosomal subunit proteins by mass spectrometry and Edman sequencing". J. Protein Chem. 22 (3): 249–58. PMID 12962325.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Andersen JS, Lam YW, Leung AK; et al. (2005). "Nucleolar proteome dynamics". Nature. 433 (7021): 77–83. doi:10.1038/nature03207. PMID 15635413.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Nakanishi K, Komatsu Y, Kogawa N, Matsushita H (2005). "Analysis of eluted peptides from type 1 diabetes-susceptible HLA class II molecules identified novel islet protein, heparin/heparan sulfate-interacting protein". Biochem. Biophys. Res. Commun. 329 (1): 356–61. doi:10.1016/j.bbrc.2005.01.144. PMID 15721314.CS1 maint: Multiple names: authors list (link)
• Stelzl U, Worm U, Lalowski M; et al. (2005). "A human protein-protein interaction network: a resource for annotating the proteome". Cell. 122 (6): 957–68. doi:10.1016/j.cell.2005.08.029. PMID 16169070.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Liu JJ, Huang BH, Zhang J; et al. (2006). "Repression of HIP/RPL29 expression induces differentiation in colon cancer cells". J. Cell. Physiol. 207 (2): 287–92. doi:10.1002/jcp.20589. PMID 16475173.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)