Ring finger protein 167

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Identifiers
Aliases
External IDs	GeneCards: [1]
Orthologs
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a
Wikidata
View/Edit Human

Ring finger protein 167 is a protein that in humans is encoded by the RNF167 gene.

Function

RNF167 is an E3 ubiquitin ligase that interacts with TSSC5 (SLC22A18; MIM 602631) and, together with UBCH6 (UBE2E1; MIM 602916), facilitates TSSC5 polyubiquitylation (Yamada and Gorbsky, 2006 [PubMed 16314844]).[supplied by OMIM, Mar 2008].

Further reading

• Lussier MP, Herring BE, Nasu-Nishimura Y, Neutzner A, Karbowski M, Youle RJ, Nicoll RA, Roche KW (November 2012). "Ubiquitin ligase RNF167 regulates AMPA receptor-mediated synaptic transmission". Proc. Natl. Acad. Sci. U.S.A. 109 (47): 19426–31. doi:10.1073/pnas.1217477109. PMC 3511152. PMID 23129617.
• Yamazaki Y, Schönherr C, Varshney GK, Dogru M, Hallberg B, Palmer RH (February 2013). "Goliath family E3 ligases regulate the recycling endosome pathway via VAMP3 ubiquitylation". EMBO J. 32 (4): 524–37. doi:10.1038/emboj.2013.1. PMC 3579141. PMID 23353890.
• van Dijk JR, Yamazaki Y, Palmer RH (April 2014). "Tumour-associated mutations of PA-TM-RING ubiquitin ligases RNF167/RNF13 identify the PA domain as a determinant for endosomal localization". Biochem. J. 459 (1): 27–36. doi:10.1042/BJ20131067. PMID 24387786.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.