SLC6A14

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Identifiers
Aliases
External IDs	GeneCards: [1]
Orthologs
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a
Wikidata
View/Edit Human

Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+) (SLC6A14) is a protein that in humans is encoded by the SLC6A14 gene.

Function

SLC6A14 is a member of the Na⁺- and Cl⁻-dependent neurotransmitter transporter family and transports both neutral and cationic amino acids in an Na⁺- and Cl⁻-dependent manner.[supplied by OMIM]

Further reading

• Ohman M, Oksanen L, Kaprio J, Koskenvuo M, Mustajoki P, Rissanen A, Salmi J, Kontula K, Peltonen L (2000). "Genome-wide scan of obesity in Finnish sibpairs reveals linkage to chromosome Xq24". J. Clin. Endocrinol. Metab. 85 (9): 3183–90. doi:10.1210/jc.85.9.3183. PMID 10999806.
• Sloan JL, Grubb BR, Mager S (2003). "Expression of the amino acid transporter ATB 0+ in lung: possible role in luminal protein removal". Am. J. Physiol. Lung Cell Mol. Physiol. 284 (1): L39–49. doi:10.1152/ajplung.00164.2002. PMID 12388375.
• Suviolahti E, Oksanen LJ, Ohman M, Cantor RM, Ridderstrale M, Tuomi T, Kaprio J, Rissanen A, Mustajoki P, Jousilahti P, Vartiainen E, Silander K, Kilpikari R, Salomaa V, Groop L, Kontula K, Peltonen L, Pajukanta P (2004). "The SLC6A14 gene shows evidence of association with obesity". J. Clin. Invest. 112 (11): 1762–72. doi:10.1172/JCI17491. PMC 281637. PMID 14660752.
• Durand E, Boutin P, Meyre D, Charles MA, Clement K, Dina C, Froguel P (2004). "Polymorphisms in the amino acid transporter solute carrier family 6 (neurotransmitter transporter) member 14 gene contribute to polygenic obesity in French Caucasians". Diabetes. 53 (9): 2483–6. doi:10.2337/diabetes.53.9.2483. PMID 15331564.
• Gupta N, Miyauchi S, Martindale RG, Herdman AV, Podolsky R, Miyake K, Mager S, Prasad PD, Ganapathy ME, Ganapathy V (2005). "Upregulation of the amino acid transporter ATB0,+ (SLC6A14) in colorectal cancer and metastasis in humans". Biochim. Biophys. Acta. 1741 (1–2): 215–23. doi:10.1016/j.bbadis.2005.04.002. PMID 15905073.