Sorting nexin-21 is a protein that in humans is encoded by the SNX21gene.[1][2][3]
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region, like some family members. The specific function of this protein has not been determined. Multiple transcript variants encoding distinct isoforms have been identified for this gene.[3]
References
↑Worby CA, Dixon JE (Dec 2002). "Sorting out the cellular functions of sorting nexins". Nat Rev Mol Cell Biol. 3 (12): 919–31. doi:10.1038/nrm974. PMID12461558.
↑Zeng W, Yuan W, Wang Y, Jiao W, Zhu Y, Huang C, Li D, Li Y, Zhu C, Wu X, Liu M (Dec 2002). "Expression of a novel member of sorting nexin gene family, SNX-L, in human liver development". Biochem Biophys Res Commun. 299 (4): 542–8. doi:10.1016/S0006-291X(02)02695-5. PMID12459172.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID14702039.
Deloukas P, Matthews LH, Ashurst J, et al. (2002). "The DNA sequence and comparative analysis of human chromosome 20". Nature. 414 (6866): 865–71. doi:10.1038/414865a. PMID11780052.
