Testican-2 is a protein that in humans is encoded by the SPOCK2gene.[1][2]
Function
Proteoglycans, which consist of a core protein and covalently linked glycosaminoglycans, are components of the extracellular matrix. SPOCK2 encodes a member of a novel Ca(2+)-binding proteoglycan family.[supplied by OMIM][2]
References
↑Vannahme C, Schübel S, Herud M, Gösling S, Hülsmann H, Paulsson M, Hartmann U, Maurer P (July 1999). "Molecular cloning of testican-2: defining a novel calcium-binding proteoglycan family expressed in brain". Journal of Neurochemistry. 73 (1): 12–20. doi:10.1046/j.1471-4159.1999.0730012.x. PMID10386950.
Nagase T, Seki N, Ishikawa K, Ohira M, Kawarabayasi Y, Ohara O, Tanaka A, Kotani H, Miyajima N, Nomura N (October 1996). "Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain". DNA Research. 3 (5): 321–9, 341–54. doi:10.1093/dnares/3.5.321. PMID9039502.
Nakada M, Miyamori H, Yamashita J, Sato H (June 2003). "Testican 2 abrogates inhibition of membrane-type matrix metalloproteinases by other testican family proteins". Cancer Research. 63 (12): 3364–9. PMID12810672.