Sandbox/0319

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FDA-Labeled Indications and Dosage (Adult)
Prophylaxis of Ischemic Complications in Unstable Angina and Non-Q-Wave Myocardial Infarction
Fragmin injection 120 IU/kg SC q12h (≤10,000 IU) for 5—8 days with concurrent Aspirin 75—165 mg PO q24h
Prophylaxis of Venous Thromboembolism Following Hip Replacement Surgery
Fragmin injection 2500 IU SC 4—8 hours POSToperatively followed by 5000 IU SC q24h for 5—10 days
OR
Fragmin injection 2500 IU SC 2 hours PREoperatively and 4—8 hours POSToperatively followed by 5000 IU SC q24h for 5—10 days
OR
Fragmin injection 5000 IU SC 10—14 hours PREoperatively and 4—8 hours POSToperatively followed by q24h for 5—10 days
Prophylaxis of Venous Thromboembolism Following Abdominal Surgery
Fragmin injection 2500 IU SC q24h PREoperatively followed by q24h for 5—10 days
OR
Fragmin injection 5000 IU SC q24h for 5—10 days (starting the evening prior to sugery) [High Risk Patient]
OR
Fragmin injection 2500 IU SC PREoperatively and 2500 IU SC 12 hours later followed by 5000 IU SC q24h for 5—10 days [High Risk Patient]
Medical Patients with Severely Restricted Mobility During Acute Illness
Fragmin injection 5000 IU SC q24h for 12—14 days
Extended Treatment of Symptomatic Venous Thromboembolism in Patients with Cancer
Fragmin injection 200 IU/kg SC q24h (≤18,000 IU) for 30 days followed by 150 IU/kg SC q24h from months 2—6