Sandbox subdural empyema
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Antimicrobial Regimen – Empiric Therapy
- Ampicillin 200 mg/kg/day IV q4h AND
- Cefotaxime 200 mg/kg/day IV q6h
- Ampicillin 200 mg/kg/day IV q4h AND
- Cefotaxime 200 mg/kg/day IV q6h OR Ceftriaxone 100 mg/kg/day IV q12h
- Vancomycin 60 mg/kg/day IV q6h (pediatric) or 2 g/day IV q12h (adult) AND
- Cefotaxime 200 mg/kg/day IV q6h (pediatric) or 12 g/day IV q4h (adult) OR Ceftriaxone 100 mg/kg/day IV q12h (pediatric) or 4 g/day IV q12h (adult) OR Cefepime 150 mg/kg/day IV q8h (pediatric) or 6 g/day IV q8h (adult)
- Ampicillin 200 mg/kg/day IV q4h AND
- Vancomycin 2 g/day IV q12h AND
- Cefotaxime 12 g/day IV q4h OR Ceftriaxone 4 g/day IV q12h OR Cefepime 6 g/day IV q8h
- Ampicillin 200 mg/kg/day IV q4h (pediatric) or 12 g/day IV q4h (adult) AND
- Vancomycin 60 mg/kg/day IV q6h (pediatric) or 2 g/day IV q12h (adult) AND
- Ceftazidime 150 mg/kg/day IV q8h (pediatric) or 6 g/day IV q8h (adult) OR Meropenem 20 mg/kg/day IV q8h (pediatric) or 3 g/day IV q8h (adult)