Sarcoma botryoides pathophysiology

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Sarcoma botryoides Microchapters
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Overview
Historical perspective
Classification
Pathophysiology
Causes
Differentiating Sarcoma botryoides from other Diseases
Epidemiology and Demographics
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Natural history, Complications, and Prognosis
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History and Symptoms
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Overview

Sarcoma botryoides, also known as embryonal rhabdomyosarcoma, is a type of rhabdomyosarcoma in the vagina of young girls, typically younger than 8. The name comes from the gross appearance of "grape bunches" (botryoid in Greek).

Pathophysiology

Under the microscope one can see rhabdomyoblasts that may contain cross-striations. Tumor cells are crowded in a distinct layer beneath the vaginal epithelium, named the cambium layer.