Secondary amyloidosis history and symptoms
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sahar Memar Montazerin, M.D.[2]Shaghayegh Habibi, M.D.[3]
Overview
Symptoms of secondary amyloidosis may vary depending on the primary disorder and the affected organs. Secondary amyloidosis most commonly presents with kidney involvement and patients usually have a positive history of periorbital edema and frothy urine.
History and Symptoms
- Symptoms of secondary amyloidosis may vary depending on the primary disorder and the affected organs.[1]
- Patients with secondary amyloidosis may have a positive history of inflammatory disorders such as familial mediterranean fever, rheumatoid arthritis, inflammatory bowel disease, and etc.
- Secondary amyloidosis most commonly presents with kidney involvement and patients usually have a positive history of periorbital edema and frothy urine.
- Abdominal mass, early satiety and other less common symptoms may be present in the case of other organ involvement.
- Other less common symptoms include:
- Abdominal pain
- Chronic diarrhea as a result of malabsorption
- Numbness in fingers and toes
References
- ↑ Lachmann, Helen J.; Goodman, Hugh J.B.; Gilbertson, Janet A.; Gallimore, J. Ruth; Sabin, Caroline A.; Gillmore, Julian D.; Hawkins, Philip N. (2007). "Natural History and Outcome in Systemic AA Amyloidosis". New England Journal of Medicine. 356 (23): 2361–2371. doi:10.1056/NEJMoa070265. ISSN 0028-4793.