Serine protease 57

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Identifiers
Aliases
External IDs	GeneCards: [1]
Orthologs
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a
Wikidata
View/Edit Human

Serine protease 57 is a protein that in humans is encoded by the PRSS57 gene.

Function

This gene encodes an arginine-specific serine protease and member of the peptidase S1 family of proteins. The encoded protein may undergo proteolytic activation before storage in azurophil granules, in neutrophil cells of the immune system. Following neutrophil activation, the protease is released into the pericellular environment, where it may play a role in defense against microbial pathogens. [provided by RefSeq, Jul 2016].

Further reading

• Perera NC, Wiesmüller KH, Larsen MT, Schacher B, Eickholz P, Borregaard N, Jenne DE (September 2013). "NSP4 is stored in azurophil granules and released by activated neutrophils as active endoprotease with restricted specificity". J. Immunol. 191 (5): 2700–7. doi:10.4049/jimmunol.1301293. PMID 23904161.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.