Small left colon syndrome

WikiDoc Resources for Small left colon syndrome
Articles
Most recent articles on Small left colon syndrome Most cited articles on Small left colon syndrome Review articles on Small left colon syndrome Articles on Small left colon syndrome in N Eng J Med, Lancet, BMJ
Media
Powerpoint slides on Small left colon syndrome Images of Small left colon syndrome Photos of Small left colon syndrome Podcasts & MP3s on Small left colon syndrome Videos on Small left colon syndrome
Evidence Based Medicine
Cochrane Collaboration on Small left colon syndrome Bandolier on Small left colon syndrome TRIP on Small left colon syndrome
Clinical Trials
Ongoing Trials on Small left colon syndrome at Clinical Trials.gov Trial results on Small left colon syndrome Clinical Trials on Small left colon syndrome at Google
Guidelines / Policies / Govt
US National Guidelines Clearinghouse on Small left colon syndrome NICE Guidance on Small left colon syndrome NHS PRODIGY Guidance FDA on Small left colon syndrome CDC on Small left colon syndrome
Books
Books on Small left colon syndrome
News
Small left colon syndrome in the news Be alerted to news on Small left colon syndrome News trends on Small left colon syndrome
Commentary
Blogs on Small left colon syndrome
Definitions
Definitions of Small left colon syndrome
Patient Resources / Community
Patient resources on Small left colon syndrome Discussion groups on Small left colon syndrome Patient Handouts on Small left colon syndrome Directions to Hospitals Treating Small left colon syndrome Risk calculators and risk factors for Small left colon syndrome
Healthcare Provider Resources
Symptoms of Small left colon syndrome Causes & Risk Factors for Small left colon syndrome Diagnostic studies for Small left colon syndrome Treatment of Small left colon syndrome
Continuing Medical Education (CME)
CME Programs on Small left colon syndrome
International
Small left colon syndrome en Espanol Small left colon syndrome en Francais
Business
Small left colon syndrome in the Marketplace Patents on Small left colon syndrome
Experimental / Informatics
List of terms related to Small left colon syndrome

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Neonatal small left colon syndrome is a cause of functional colon obstruction in newborn infants. Small left colon sydrome is subset of meconium plug syndrome in which an enema demonstrates an apparent transition zone between the dilated and the normal-to-decreased caliber distal colon at the splenic flexure. There is a high association of maternal diabetes.

Patient #1: Failure to pass meconium

• 
• 
• 
• 
• 

Small left colon syndrome must be differentiated from other diseases that cause a failure to pass meconium or abdominal distension in infants, including meconium plug syndrome, and congenital hypothyroidism.

Disease	Prominent clinical features	Radiological findings
Meconium plug syndrome	Transient intestinal obstruction for 1-2 days after birth. Obstruction is functional due to dilated colon and delayed passage of feces. Usually seen in premature infants.	Abdominal x-ray with contrast showing inspissated meconium in the intestine, proximal to the colon - Case courtesy of Radswiki, Radiopaedia.org, rID 11606
Small left colon syndrome	Reduced caliber of the colon starting from splenic flexure and going down, causing intestinal obstruction. Characterized by a sudden change of the colon diameter. Usually associated with gestational diabetes.	Abdominal x-ray with contrast, shows decreased caliber of the descending and sigmoid colon, loss of haustration along with filling defects corresponding to retained feces - Case courtesy of Dr Eric F Greif, Radiopaedia.org, rID 30024
Distal small intestine/colon atresia	Failure to pass meconium due to failure of intestine recanalization. Proximal lesions have an earlier onset of symptoms than distal lesions. Colonic atresia may affect normal children or may be associated with other abnormalities as Hirschsprung's disease or gastroschisis.	Normal appearing colon that is small and unused. Contrast fills the whole colon and passes to the ileum - Case courtesy of A.Prof Frank Gaillard, Radiopaedia.org, rID 5959
Meconium ileus	Intestinal obstruction due to inspissation of meconium in the distal ileum. Most cases of meconium ileus are secondary to cystic fibrosis. Typically presents with failure to pass meconium and abdominal distension with or without vomiting. Meconium ileus may first present with complications, including perforation and volvulus.	Contrast enema shows inspissated meconium starting from the mid-sigmoid colon and going up till the splenic flexure. The colon is normal in diameter, ruling out microcolon - Case courtesy of Dr Michael Sargent, Radiopaedia.org, rID 6009
Congenital hypothyroidism	Most infants are born asymptomatic. Symptoms, if present, may include, but not limited to: Macroglossia Hoarse cry Umbilical hernia Puffy facies Increased head circumference Hypothermia