Sodium aurothiosulfate

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Sodium aurothiosulfate
Clinical data
Routes of; administration	Intramuscular injection
ATC code	M01CB02 (WHO) ;
Identifiers
	IUPAC name trisodium dithiosulphate aurate(I), dihydrate;
CAS Number	18497-75-1 ;
PubChem CID	170028;
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
Formula	AuNa3O6S4
Molar mass	332.08452 g/mol
(verify)

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Sodium aurothiosulfate is the inorganic compound with the formula Na₃Au(S₂O₃)₂·2H₂O. This salt contains an anionic linear coordination complex of gold(I) bound to two thiosulfate ligands.^[1]^[2] Like several other gold compounds, this species is used as an antirheumatic.^[3]The first placebo-controlled trial was probably conducted in 1931, when sanocrysin was compared with distilled water for the treatment of tuberculosis.^[4]

References

↑ Baggio, R (1973). "Crystal and molecular structure of trisodium dithiosulphate aurate(I), dihydrate, Na3[Au(S2O3)2],2H2O". Journal of Inorganic and Nuclear Chemistry. 35 (9): 3191. doi:10.1016/0022-1902(73)80019-3.
↑ Tobön-Zapata, G (1997). "Vibrational spectrum of Sanocrysin". Spectrochimica Acta Part a Molecular and Biomolecular Spectroscopy. 53 (2): 183. doi:10.1016/S1386-1425(97)83024-7.
↑ Shaw, III, C. F. (1999). "Gold-Based Therapeutic Agents". Chemical Reviews. 99 (9): 2589–600. doi:10.1021/cr980431o. PMID 11749494.
↑ Ethical and regulatory aspects of clinical research: readings and commentary, Ezekiel J. Emanuel, Johns Hopkins University Press, 2003, p 140

[1] Baggio, R (1973). "Crystal and molecular structure of trisodium dithiosulphate aurate(I), dihydrate, Na3[Au(S2O3)2],2H2O". Journal of Inorganic and Nuclear Chemistry. 35 (9): 3191. doi:10.1016/0022-1902(73)80019-3.

[2] Tobön-Zapata, G (1997). "Vibrational spectrum of Sanocrysin". Spectrochimica Acta Part a Molecular and Biomolecular Spectroscopy. 53 (2): 183. doi:10.1016/S1386-1425(97)83024-7.

[shaw-3] Shaw, III, C. F. (1999). "Gold-Based Therapeutic Agents". Chemical Reviews. 99 (9): 2589–600. doi:10.1021/cr980431o. PMID 11749494.

[4] Ethical and regulatory aspects of clinical research: readings and commentary, Ezekiel J. Emanuel, Johns Hopkins University Press, 2003, p 140

[1]

[2]

[3]

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Clinical data


Routes of administration	Intramuscular injection
ATC code	M01CB02 (WHO)
Identifiers
IUPAC name trisodium dithiosulphate aurate(I), dihydrate
CAS Number	18497-75-1^Y
PubChem CID	170028
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
Formula	AuNa₃O₆S₄
Molar mass	332.08452 g/mol
(verify)

Sodium aurothiosulfate

Overview

References

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