Soft tissue sarcoma epidemiology and demographics

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Template:Soft tissue sarcoma Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Rim Halaby, M.D. [2]

Overview

Soft tissue sarcomas are relatively uncommon cancers. They account for less than 1% of all new cancer cases each year.[1]

Epidemiology

Incidence

  • The estimated number of new cases of soft tissue sarcoma in the United States is approximately 12,000.[2]
  • The estimated incidence of soft tissue sarcoma worldwide is 1.8 to 5 per 100,000 per year.[3]

Age

Soft tissue sarcomas are more commonly found in older patients (>50 years old) although in children and adolescents under age 20, certain histologies are common (rhabdomyosarcoma).

Percent Distribution of Soft Tissue Sarcoma by Histology

  • Fibrosarcoma: 6.9%
  • Infantile fibrosarcoma: 0.2%
  • Fibrous histiocytoma, malignant: 9.2%
  • Dermatofibrosarcoma: 3.6%
  • Liposarcoma: 17.1%
  • Leiomyosarcoma: 13.2%
  • Rhabdomyosarcoma: 3.1%
  • Embryonal rhabdomyosarcoma: 1.3%
  • Hemangiosarcoma: 3.7%
  • Hemangiopericytoma, malignant: 0.5%
  • Kaposi sarcoma: 0.8%
  • Malignant peripheral nerve sheath tumor: 1.6%
  • Malignant neurilemmoma: 0.2%
  • Neuroblastoma: 0.6%
  • Synovial sarcoma: 4.8%

References

  1. ↑ Zahm SH, Fraumeni JF (1997). "The epidemiology of soft tissue sarcoma". Semin Oncol. 24 (5): 504–14. PMID 9344316.
  2. ↑ American Cancer Society: Cancer Facts and Figures 2014. Atlanta, Ga: American Cancer Society, 2014. Available online . Last accessed May 21, 2014.
  3. ↑ Wibmer C, Leithner A, Zielonke N, Sperl M, Windhager R (2010). "Increasing incidence rates of soft tissue sarcomas? A population-based epidemiologic study and literature review". Ann Oncol. 21 (5): 1106–11. doi:10.1093/annonc/mdp415. PMID 19858086.

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