Sperm associated antigen 5

Sperm associated antigen 5
Identifiers
Symbols	SPAG5 ; DEEPEST; MAP126; hMAP126
External IDs	Template:MGI HomoloGene: 4718
Gene ontology Cellular component Template:GNF GO Biological process Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO
RNA expression pattern
File:PBB GE SPAG5 203145 at tn.png
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Sperm associated antigen 5, also known as SPAG5, is a human gene.

This gene encodes a protein associated with the mitotic spindle apparatus. The encoded protein may be involved in the functional and dynamic regulation of mitotic spindles.

Further reading

• Howard L, Nelson KK, Maciewicz RA, Blobel CP (1999). "Interaction of the metalloprotease disintegrins MDC9 and MDC15 with two SH3 domain-containing proteins, endophilin I and SH3PX1". J. Biol. Chem. 274 (44): 31693–9. PMID 10531379.CS1 maint: Multiple names: authors list (link)
• Shao X, Xue J, van der Hoorn FA (2001). "Testicular protein Spag5 has similarity to mitotic spindle protein Deepest and binds outer dense fiber protein Odf1". Mol. Reprod. Dev. 59 (4): 410–6. doi:10.1002/mrd.1047. PMID 11468777.CS1 maint: Multiple names: authors list (link)
• Chang MS, Huang CJ, Chen ML; et al. (2001). "Cloning and characterization of hMAP126, a new member of mitotic spindle-associated proteins". Biochem. Biophys. Res. Commun. 287 (1): 116–21. doi:10.1006/bbrc.2001.5554. PMID 11549262.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Mack GJ, Compton DA (2002). "Analysis of mitotic microtubule-associated proteins using mass spectrometry identifies astrin, a spindle-associated protein". Proc. Natl. Acad. Sci. U.S.A. 98 (25): 14434–9. doi:10.1073/pnas.261371298. PMID 11724960.
• Gruber J, Harborth J, Schnabel J; et al. (2003). "The mitotic-spindle-associated protein astrin is essential for progression through mitosis". J. Cell. Sci. 115 (Pt 21): 4053–9. PMID 12356910.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Gerhard DS, Wagner L, Feingold EA; et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Le XF, Lammayot A, Gold D; et al. (2005). "Genes affecting the cell cycle, growth, maintenance, and drug sensitivity are preferentially regulated by anti-HER2 antibody through phosphatidylinositol 3-kinase-AKT signaling". J. Biol. Chem. 280 (3): 2092–104. doi:10.1074/jbc.M403080200. PMID 15504738.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Yang YC, Hsu YT, Wu CC; et al. (2006). "Silencing of astrin induces the p53-dependent apoptosis by suppression of HPV18 E6 expression and sensitizes cells to paclitaxel treatment in HeLa cells". Biochem. Biophys. Res. Commun. 343 (2): 428–34. doi:10.1016/j.bbrc.2006.02.166. PMID 16546135.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Nousiainen M, Silljé HH, Sauer G; et al. (2006). "Phosphoproteome analysis of the human mitotic spindle". Proc. Natl. Acad. Sci. U.S.A. 103 (14): 5391–6. doi:10.1073/pnas.0507066103. PMID 16565220.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Cheng TS, Hsiao YL, Lin CC; et al. (2007). "hNinein is required for targeting spindle-associated protein Astrin to the centrosome during the S and G2 phases". Exp. Cell Res. 313 (8): 1710–21. doi:10.1016/j.yexcr.2007.02.023. PMID 17383637.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)