Statin induced myopathy laboratory tests
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Rim Halaby
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Overview
When a patient presents with symptoms suggestive of statin induced myopathy, the diagnostic evaluation should include measuring the level of creatine kinase. It is useful to obtain the levels of TSH, ESR and vitamin D levels as well in order to rule out other diseases that can cause myalgia.[1][2]
Laboratory Tests
A proper evaluation should be done by checking the following:
- The level of creatine kinase compared to the upper limit of normal (ULN)
- TSH level as hypothyroidism is a risk factor for statin induced myopathy.[1]
- The level of vitamin D[2]
References
- ↑ 1.0 1.1 Harper CR, Jacobson TA (2010). "Evidence-based management of statin myopathy". Curr Atheroscler Rep. 12 (5): 322–30. doi:10.1007/s11883-010-0120-9. PMID 20628837.
- ↑ 2.0 2.1 Fernandez G, Spatz ES, Jablecki C, Phillips PS (2011). "Statin myopathy: a common dilemma not reflected in clinical trials". Cleve Clin J Med. 78 (6): 393–403. doi:10.3949/ccjm.78a.10073. PMID 21632911.