Subependymal giant cell astrocytoma secondary prevention
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1], Associate Editor(s)-in-Chief: Sujit Routray, M.D. [2], Ifeoma Odukwe, M.D. [3]
Overview
Effective measures for the secondary prevention of subependymal giant cell astrocytoma include brain imaging, preferably magnetic resonance imaging with and without contrast, which should be performed every 1 to 3 years until the age of 25 years in every patient with tuberous sclerosis.
Secondary Prevention
Effective measures for the secondary prevention of subependymal giant cell astrocytoma include:[1]
- Brain imaging, preferably magnetic resonance imaging with and without contrast, should be performed every 1 to 3 years until the age of 25 years in every patient with tuberous sclerosis.
- Follow-up magnetic resonance imaging may not be needed every 3 years, but intervals may be prolonged in the presence of a stable lesion and a stable patient.
- Screening and follow-up scans frequency should be tailored according to various clinical factors.
- New onset of symptoms such as headache, visual complaints, nausea, vomiting, or increase in seizure activity should warrant an earlier MRI scan.
- Similarly, a growing subependymal giant cell astrocytoma should prompt a more frequent clinical and radiological follow-up.
References
- ↑ Roth, Jonathan; Roach, E. Steve; Bartels, Ute; Jóźwiak, Sergiusz; Koenig, Mary Kay; Weiner, Howard L.; Franz, David N.; Wang, Henry Z. (2013). "Subependymal Giant Cell Astrocytoma: Diagnosis, Screening, and Treatment. Recommendations From the International Tuberous Sclerosis Complex Consensus Conference 2012". Pediatric Neurology. 49 (6): 439–444. doi:10.1016/j.pediatrneurol.2013.08.017. ISSN 0887-8994.