Submucosa

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

WikiDoc Resources for Submucosa
Articles
Most recent articles on Submucosa Most cited articles on Submucosa Review articles on Submucosa Articles on Submucosa in N Eng J Med, Lancet, BMJ
Media
Powerpoint slides on Submucosa Images of Submucosa Photos of Submucosa Podcasts & MP3s on Submucosa Videos on Submucosa
Evidence Based Medicine
Cochrane Collaboration on Submucosa Bandolier on Submucosa TRIP on Submucosa
Clinical Trials
Ongoing Trials on Submucosa at Clinical Trials.gov Trial results on Submucosa Clinical Trials on Submucosa at Google
Guidelines / Policies / Govt
US National Guidelines Clearinghouse on Submucosa NICE Guidance on Submucosa NHS PRODIGY Guidance FDA on Submucosa CDC on Submucosa
Books
Books on Submucosa
News
Submucosa in the news Be alerted to news on Submucosa News trends on Submucosa
Commentary
Blogs on Submucosa
Definitions
Definitions of Submucosa
Patient Resources / Community
Patient resources on Submucosa Discussion groups on Submucosa Patient Handouts on Submucosa Directions to Hospitals Treating Submucosa Risk calculators and risk factors for Submucosa
Healthcare Provider Resources
Symptoms of Submucosa Causes & Risk Factors for Submucosa Diagnostic studies for Submucosa Treatment of Submucosa
Continuing Medical Education (CME)
CME Programs on Submucosa
International
Submucosa en Espanol Submucosa en Francais
Business
Submucosa in the Marketplace Patents on Submucosa
Experimental / Informatics
List of terms related to Submucosa

In the gastrointestinal tract, the submucosa is the layer of loose connective tissue that supports the mucosa, as well as joins the mucosa to the bulk of underlying smooth muscle (fibers running circularly within layer of longitudinal muscle).

Contents

Blood vessels, lymphatic vessels, and nerves (all supplying the mucosa) will run through here.

Tiny parasympathetic ganglia are scattered around forming the submucosal plexus (or "Meissner's plexus") where preganglionic parasympathetic neurons synapse with postganglionic nerve fibers that supply the muscularis mucosae.

The submucosa in endoscopy

Identification of the submucosa plays an important role in diagnostic and therapeutic endoscopy, where special fibre-optic cameras are used to perform procedures on the gastrointestinal tract. Abnormalities of the submucosa, such as gastrointestinal stromal tumors, usually show integrity of the mucosal surface.

The submucosa is also identified in endoscopic ultrasound to identify the depth of tumours and to identify other abnormalities. An injection of dye, saline, or epinephrine into the submucosa is imperative in the safe removal of certain polyps.

Endoscopic mucosal resection involves removal of the mucosal layer, and in order to be done safely, a submucosal injection of dye is performed to ensure integrity at the beginning of the procedure.

See also

• Small intestinal submucosa

Additional images

• 
  Bladder.
• 
  Stomach.
• 
  Section of the human esophagus. Moderately magnified.
• 
  Vertical section of bladder wall.
• 
  General structure of the gut wall showing the submucosa.

External links

• Template:UCDavisOrganology - "Mammal, whole system (LM, Low)"
• Template:EMedicineDictionary
• Histology image: 00102loa – Histology Learning System at Boston University - "Tissues, Layers, and Organs: transverse section of rat gut"
• Essentials of Human Physiology by Thomas M. Nosek. Section 6/6ch1/s6ch1_9.
• Template:OklahomaHistology
• Template:AnatomyAtlasesMicroscopic - "Duodenum and Jejunum"
• Histology at edteched.uottawa.ca

Template:WikiDoc Sources