Sudden infant death syndrome causes
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Vamsikrishna Gunnam M.B.B.S [2]
Overview
Sudden infant death syndrome (SIDS) may be caused by genetic mutations, brainstem abnormality, airflow obstruction, and infections.
Causes
Common Causes
Common causes of Sudden infant death syndrome (SIDS) may include:[1][2][3]
- Genetic mutations
- Brain stem anomalies
- Cardiac ion channel defects
Less Common Causes
Less common causes of Sudden infant death syndrome (SIDS) include:
- Position of the infant especially in the prone position
- Infections
Causes by Organ System
| Cardiovascular | Cardiac ion channel defects |
| Chemical/Poisoning | No underlying causes |
| Dental | No underlying causes |
| Dermatologic | No underlying causes |
| Drug Side Effect | No underlying causes |
| Ear Nose Throat | No underlying causes |
| Endocrine | No underlying causes |
| Environmental | Prone position |
| Gastroenterologic | No underlying causes |
| Genetic | Genetic mutations in SCN5A, SCN4A, KCNQ1, KCNH2, RYR2 |
| Hematologic | No underlying causes |
| Iatrogenic | No underlying causes |
| Infectious Disease | Infections |
| Musculoskeletal/Orthopedic | No underlying causes |
| Neurologic | Brain stem anomalies |
| Nutritional/Metabolic | No underlying causes |
| Obstetric/Gynecologic | No underlying causes |
| Oncologic | No underlying causes |
| Ophthalmologic | No underlying causes |
| Overdose/Toxicity | No underlying causes |
| Psychiatric | No underlying causes |
| Pulmonary | No underlying causes |
| Renal/Electrolyte | No underlying causes |
| Rheumatology/Immunology/Allergy | No underlying causes |
| Sexual | No underlying causes |
| Trauma | No underlying causes |
| Urologic | No underlying causes |
| Miscellaneous | No underlying causes |
- 0
References
- ↑ Van Norstrand DW, Valdivia CR, Tester DJ, Ueda K, London B, Makielski JC; et al. (2007). "Molecular and functional characterization of novel glycerol-3-phosphate dehydrogenase 1 like gene (GPD1-L) mutations in sudden infant death syndrome". Circulation. 116 (20): 2253–9. doi:10.1161/CIRCULATIONAHA.107.704627. PMC 3332545. PMID 17967976.
- ↑ Tan BH, Pundi KN, Van Norstrand DW, Valdivia CR, Tester DJ, Medeiros-Domingo A; et al. (2010). "Sudden infant death syndrome-associated mutations in the sodium channel beta subunits". Heart Rhythm. 7 (6): 771–8. doi:10.1016/j.hrthm.2010.01.032. PMC 2909680. PMID 20226894.
- ↑ Schwartz PJ, Stramba-Badiale M, Segantini A, Austoni P, Bosi G, Giorgetti R; et al. (1998). "Prolongation of the QT interval and the sudden infant death syndrome". N Engl J Med. 338 (24): 1709–14. doi:10.1056/NEJM199806113382401. PMID 9624190.