BTB/POZ domain-containing protein TNFAIP1 is a protein that in humans is encoded by the TNFAIP1gene.[1][2][3]
This gene was identified as a gene whose expression can be induced by the tumor necrosis factor alpha (TNF) in umbilical vein endothelial cells. Studies of a similar gene in mouse suggest that the expression of this gene is developmentally regulated in a tissue-specific manner.[3]
References
↑Dixit VM, Green S, Sarma V, Holzman LB, Wolf FW, O'Rourke K, Ward PA, Prochownik EV, Marks RM (Mar 1990). "Tumor necrosis factor-alpha induction of novel gene products in human endothelial cells including a macrophage-specific chemotaxin". J Biol Chem. 265 (5): 2973–8. PMID2406243.
Wolf FW, Marks RM, Sarma V, et al. (1992). "Characterization of a novel tumor necrosis factor-alpha-induced endothelial primary response gene". J. Biol. Chem. 267 (2): 1317–26. PMID1370465.
Pandey A, Shao H, Marks RM, et al. (1995). "Role of B61, the ligand for the Eck receptor tyrosine kinase, in TNF-alpha-induced angiogenesis". Science. 268 (5210): 567–9. doi:10.1126/science.7536959. PMID7536959.