TSPO (protein)
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translocator protein (18kDa) | |
---|---|
Identifiers | |
Symbol | TSPO |
Alt. symbols | BZRP |
Entrez | 706 |
HUGO | 1158 |
OMIM | 109610 |
RefSeq | NM_007311 |
UniProt | P30536 |
Other data | |
Locus | Chr. 22 q13.3 |
TSPO (Translocator Protein), also known as the peripheral benzodiazepine receptor (PBR), is a 18 kDa mitochondrial membrane protein.[1] Among its many functions are regulation of steroidogenesis and apoptosis.[2]
References
- ↑ Papadopoulos V, Baraldi M, Guilarte TR, Knudsen TB, Lacapere JJ, Lindemann P, Norenberg MD, Nutt D, Weizman A, Zhang MR, Gavish M (2006). "Translocator protein (18kDa): new nomenclature for the peripheral-type benzodiazepine receptor based on its structure and molecular function". Trends Pharmacol Sci. 27 (8): 402–9. PMID 16822554.
- ↑ Casellas P, Galiegue S, Basile AS (2002). "Peripheral benzodiazepine receptors and mitochondrial function". Neurochem Int. 40 (6): 475–86. PMID 11850104.
External links
- TSPO+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)
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