Tata-box binding protein associated factor 7 like

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Identifiers
Aliases
External IDs	GeneCards: [1]
Orthologs
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a
Wikidata
View/Edit Human

TATA-box binding protein associated factor 7 like is a protein that in humans is encoded by the TAF7L gene.

Function

This gene is similar to a mouse gene that encodes a TATA box binding protein-associated factor, and shows testis-specific expression. The encoded protein could be a spermatogenesis-specific component of the DNA-binding general transcription factor complex TFIID. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009].

Further reading

• Stouffs K, Willems A, Lissens W, Tournaye H, Van Steirteghem A, Liebaers I (April 2006). "The role of the testis-specific gene hTAF7L in the aetiology of male infertility". Mol. Hum. Reprod. 12 (4): 263–7. doi:10.1093/molehr/gal020. PMID 16597641.
• Akinloye O, Gromoll J, Callies C, Nieschlag E, Simoni M (October 2007). "Mutation analysis of the X-chromosome linked, testis-specific TAF7L gene in spermatogenic failure". Andrologia. 39 (5): 190–5. doi:10.1111/j.1439-0272.2007.00789.x. PMID 17714218.
• Yazarloo F, Shirkoohi R, Mobasheri MB, Emami A, Modarressi MH (March 2013). "Expression analysis of four testis-specific genes AURKC, OIP5, PIWIL2 and TAF7L in acute myeloid leukemia: a gender-dependent expression pattern". Med. Oncol. 30 (1): 368. doi:10.1007/s12032-012-0368-8. PMID 23292864.
• Oh HR, An CH, Yoo NJ, Lee SH (July 2015). "Frameshift mutations of TAF7L gene, a core component for transcription by RNA polymerase II, in colorectal cancers". Pathol. Oncol. Res. 21 (3): 849–50. doi:10.1007/s12253-014-9832-4. PMID 25098277.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.