Tramadol precautions
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
List of precautions
General
Pediatric Use
Geriatric Use
Acute Abdominal Conditions
Use in Renal Disease
Use in Hepatic Disease
General
The recommended dose of Tramadol should not be exceeded.
Do not co-administer Tramadol with other tramadol or acetaminophen-containing products. Return to top
Pediatric Use
The safety and effectiveness of Tramadol has not been studied in the pediatric population.
Geriatric Use
In general, dose selection for an elderly patient should be cautious, reflecting the greater frequency of decreased hepatic, renal, or cardiac function; of concomitant disease and multiple drug therapy. Return to top
Acute Abdominal Conditions
The administration of Tramadol may complicate the clinical assessment of patients with acute
abdominal conditions. Return to top
Use in Renal Disease
Tramadol has not been studied in patients with impaired renal function. Experience with tramadol
suggest that impaired renal function results in a decreased rate and extent of excretion of tramadol and its active metabolite, M1. In patients with creatinine clearances of less than 30 mL/min, it is
recommended that the dosing interval of Tramadol be increased not to exceed 2 tablets every 12
hours. Return to top
Use in Hepatic Disease
Tramadol has not been studied in patients with impaired hepatic function. The use of Tramadol in
patients with hepatic impairment is not recommended. Return to top
Adapted from the FDA Package Insert.