Transmembrane protein 44

VALUE_ERROR (nil)
Identifiers
Aliases
External IDs	GeneCards: [1]
Orthologs
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a
Wikidata
View/Edit Human

Transmembrane protein 44 is a protein that in humans is encoded by the TMEM44 gene.

Gene

mRNA sequence of the TMEM44 gene is 1483 base pairs long, with 13 exons.

Locus

TMEM44 gene is located at the end of the long arm of chromosome 3 in humans (Homo sapiens).

File:Tmem44.png

TMEM44 gene on human chromosome 3

Protein

TMEM44 is 428 amino acids in length. The molecular weight of the protein is 47.1kDa, and its formula is C₂₀₈₆H₃₃₁₅N₅₈₅O₆₁₁S₂₂, with a total of 6619 atoms. TMEM44 is predicted to be integrated in the plasma membrane of the endoplasmic reticulum.

Expression

There is a overall low level expression of TMEM44 protein throughout the developmental stages of an organism.

Transcripts

There are 12 isoforms of TMEM44 including isoform a, isoform b, isoform c, isoform d, isoform X1, isoform X2, isoform X3, isoform X4, isoform X5, isoform X6, isoform X7, isoform X8.

Transmembrane Region Allocation

There are seven predicted transmembrane domains in TMEM44 protein.

File:TMEM44 posterior probabilities.png

Phobius posterior probabilities of human TMEM44 protein

Interacting Proteins

GSK3B (Glycogen synthase kinase 3 beta) is a protein predicted to physically interact with TMEM44.

Post-Translational Modification

TMEM44 is predicted to undergo threonine, tyrosine and serine phosphorylations.

File:TMEM44 Phospho.png

Predicted phosphorylation sites in human TMEM44 protein

Orthologs

TMEM44 orthologs includes groups such as amphibians, birds, fish, mammals.

Paralogs

Predicted paralogous proteins of TMEM44 are C9IZ85, F8WCY1, F8WE47, H7C3X7, J3KQW3, Q6PL43, and Q96I73.