Transposition of the great vessels epidemiology and demographics

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Dextro-transposition of the great arteries
L-transposition of the great arteries
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: Priyamvada Singh, M.B.B.S. [2]; Cafer Zorkun, M.D., Ph.D. [3]; Keri Shafer, M.D. [4]; Kristin Feeney, B.S. [5]

Overview

The prevalence of TPA is approximately 47 per 100,000 individuals worldwide. TGA accounts for 5-7 percent of all congenital heart disease and 20 percent of cyanotic heart disease. There is no racial predilection to transposition of great vessels. Transposition of the great arteries has a 60-70% male predominance.

Epidemiology

Incidence

• Transposition of the great arteries TGA is one of the commonest cyanotic congenital heart defects present in the first 24 hours of life.
• The overall annual incidence of TGA is 20-30 per 100,000 live births.
• TGA represents 5-7% of all congenital heart disease and 20% of cyanotic disease.

Demographics

Gender

• Boys outnumber girls with an approximate ratio of 2:1.

Race

• There is no racial predilection to transposition of great vessels.