Tyzzer's disease

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

WikiDoc Resources for Tyzzer's disease
Articles
Most recent articles on Tyzzer's disease Most cited articles on Tyzzer's disease Review articles on Tyzzer's disease Articles on Tyzzer's disease in N Eng J Med, Lancet, BMJ
Media
Powerpoint slides on Tyzzer's disease Images of Tyzzer's disease Photos of Tyzzer's disease Podcasts & MP3s on Tyzzer's disease Videos on Tyzzer's disease
Evidence Based Medicine
Cochrane Collaboration on Tyzzer's disease Bandolier on Tyzzer's disease TRIP on Tyzzer's disease
Clinical Trials
Ongoing Trials on Tyzzer's disease at Clinical Trials.gov Trial results on Tyzzer's disease Clinical Trials on Tyzzer's disease at Google
Guidelines / Policies / Govt
US National Guidelines Clearinghouse on Tyzzer's disease NICE Guidance on Tyzzer's disease NHS PRODIGY Guidance FDA on Tyzzer's disease CDC on Tyzzer's disease
Books
Books on Tyzzer's disease
News
Tyzzer's disease in the news Be alerted to news on Tyzzer's disease News trends on Tyzzer's disease
Commentary
Blogs on Tyzzer's disease
Definitions
Definitions of Tyzzer's disease
Patient Resources / Community
Patient resources on Tyzzer's disease Discussion groups on Tyzzer's disease Patient Handouts on Tyzzer's disease Directions to Hospitals Treating Tyzzer's disease Risk calculators and risk factors for Tyzzer's disease
Healthcare Provider Resources
Symptoms of Tyzzer's disease Causes & Risk Factors for Tyzzer's disease Diagnostic studies for Tyzzer's disease Treatment of Tyzzer's disease
Continuing Medical Education (CME)
CME Programs on Tyzzer's disease
International
Tyzzer's disease en Espanol Tyzzer's disease en Francais
Business
Tyzzer's disease in the Marketplace Patents on Tyzzer's disease
Experimental / Informatics
List of terms related to Tyzzer's disease

Tyzzer's disease is a contagious bacterial disease in rats and gerbils. It is caused by Clostridium piliforme, formerly known as Bacillus piliformis, a spore-forming bacterium.

It is transmitted horizontally through the fecal-oral route. Animals that carry the bacterium are usually asymptomatic, but a clinical syndrome may be seen in recently weaned rats.

Nonspecific signs such as anorexia, lethargy, emaciation, ruffled fur, or sudden death without clinical signs may be observed. Mucoid, bloody diarrhea may also be seen. On necropsy, animals may have megaileus. Many other organs, including liver, cecum, colon, and heart, can have characteristic pathologic lesions. Histopathologic observation of bacilli in target organs is diagnostic, and best obtained using a Warthin-Starry silver or Giemsa stain. There is no recommended treatment other than supportive care. Antibiotics effective against Clostridia spp. may be used.

References

Template:Veterinary-med-stub