Unstable angina non ST elevation myocardial infarction complications of bleeding and transfusion incidence

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Unstable angina non ST elevation myocardial infarction complications of bleeding and transfusion incidence On the Web

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Template:MWT; Cafer Zorkun, M.D., Ph.D. [2]; Varun Kumar, M.B.B.S.; Lakshmi Gopalakrishnan, M.B.B.S.

Incidence

  • The reported incidence of major bleeding events in the ACS period varies significantly across clinical trials with best estimates between 1000 and 14000 per 100,000.[1][2][3][4]
  • Differences in individual patient’s propensity to experience a bleeding event may contribute to the observed variance in bleeding incidence for NSTEMI patients.[3][4]
  • The existence of multiple bleeding definitions accounts in part for the disparity of the reported incidence of bleeding complications among NSTEMI patients.[3][4]

References

  1. Popma JJ, Satler LF, Pichard AD, Kent K, Campbell A, Clark C, Merritt A, Leon MB. Vascular complications after balloon and new device angioplasty. Circulation. 1993;88:1569–1578.
  2. Stone GW, Grines CL, Cox DA, Garcia E, Tcheng J, Griffin J, Stuckey T, Turco M, Carroll M, Lansky A. Comparison of angioplasty with stenting, with or without abciximab, in acute myocardial infarction. N Engl J Med. 2002;346:957–966.
  3. 3.0 3.1 3.2 Anderson JL, Adams CD, Antman EM, Bridges CR, Califf RM, Casey DE Jr, Chavey WE II, Fesmire FM, Hochman JS, Levin TN, Lincoff AM, Peterson ED, Theroux P, Wenger NK, Wright RS. ACC/AHA 2007 guidelines for the management of patients with unstable angina/non–ST-elevation myocardial infarction: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise the 2002 Guidelines for the Management of Patients With Unstable Angina/Non–ST-Elevation Myocardial Infarction). Circulation 2007 116: e148 – e304. PMID 17679616
  4. 4.0 4.1 4.2 Anderson JL, Adams CD, Antman EM, Bridges CR, Califf RM, Casey DE Jr, Chavey WE II, Fesmire FM, Hochman JS, Levin TN, Lincoff AM, Peterson ED, Theroux P, Wenger NK, Wright RS. Correction of ACC/AHA 2007 guidelines for the management of patients with unstable angina/non–ST-elevation myocardial infarction: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise the 2002 Guidelines for the Management of Patients With Unstable Angina/Non–ST-Elevation Myocardial Infarction). J Am Coll Cardiol. 2008 Mar 4; 51(9): 974. PMID 17692738


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