Vertebrobasilar insufficiency medical therapy
Vertebrobasilar insufficiency
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Differentiating Vertebrobasilar insufficiency from other Diseases |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
In the recent decades, interventional therapy became more and more important with the medical therapy as the foundation of the whole treatment.Open surgery is rarely used because its high risk of complication comparing with the catheter-based therapy.
Medical Therapy
The principle of medical therapy is reducing the atherosclerotic and thrombotic risk. 1.Aspirin (75 to 325 mg daily) is strongly recommended to prevent ischemic events, if there is no contraindications. 2.If the patient is suitable to accept asprin due to contraindictions, clopidogrel (75 mg daily) or ticlopidine (250 mg twice daily) is suggested to treat the atherosclerosis of the extracranial vertebral arteries. 3.Three schemes is suggested to treat the patients with persisitently ischemic stroke or TIA due to extracranial vertebral atherosclerosis.
- (1).Aspirin (81 to 325 mg daily)
- (2).Aspirin (81 to 325 mg daily) combinated with the extended-release dipyridamole (25 and 200 mg twice daily)
- (3).clopidogrel (75 mg daily).[1]
References
- ↑ Brott TG, Halperin JL, Abbara S, Bacharach JM, Barr JD, Bush RL et al. (2013) 2011 ASA/ACCF/AHA/AANN/AANS/ACR/ASNR/CNS/SAIP/SCAI/SIR/SNIS/SVM/SVS guideline on the management of patients with extracranial carotid and vertebral artery disease: executive summary: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines, and the American Stroke Association, American Association of Neuroscience Nurses, American Association of Neurological Surgeons, American College of Radiology, American Society of Neuroradiology, Congress of Neurological Surgeons, Society of Atherosclerosis Imaging and Prevention, Society for Cardiovascular Angiography and Interventions, Society of Interventional Radiology, Society of NeuroInterventional Surgery, Society for Vascular Medicine, and Society for Vascular Surgery. Developed in collaboration with the American Academy of Neurology and Society of Cardiovascular Computed Tomography. Catheter Cardiovasc Interv 81 (1):E76-123. DOI:10.1002/ccd.22983 PMID: 23281092