WBR277

Author	[[PageAuthor::Sapan Patel M.B.B.S]]
Exam Type	ExamType::USMLE Step 3
Main Category	MainCategory::Community Medical Health Center, MainCategory::Primary Care Office
Sub Category	SubCategory::Pediatrics
Prompt	[[Prompt::Physician is called to see a newborn in the nursery because the nurse is concerned that the baby have single crease in the palm of the hand, small ears, small mouth, upward slanting eyes, wide space between the first and second toes, short hands with short fingers. Which of the following sign is most likely associated in this newborn?]]
Answer A	AnswerA::Café au lait spots
Answer A Explanation	AnswerAExp::Incorrect- This newborn is showing signs of Down syndrome. Café au lait spots are associated with neurofibromatosis.
Answer B	AnswerB::High arched palate
Answer B Explanation	AnswerBExp::Incorrect- This newborn is showing signs of Down syndrome. High arched palates are associated with fragile X syndrome.
Answer C	AnswerC::Ambiguous genitalia
Answer C Explanation	AnswerCExp::Incorrect- This newborn is showing signs of Down syndrome. Ambiguous genitalia are commonly seen in CAH.
Answer D	AnswerD::Hypotonia
Answer D Explanation	AnswerDExp::Correct- See explanation.
Answer E	AnswerE::Club feet
Answer E Explanation	AnswerEExp::Incorrect- This newborn is showing signs of Down syndrome.
Right Answer	RightAnswer::D
Explanation	[[Explanation::EXPLANATION: The most common finding in a newborn with Down syndrome is hypotonia. Other common findings include single palmar crease, flat facial profile, macroglossia, and wide space between the first and second toes. Hypotonia in the newborn period should prompt close evaluation and follow-up. EDUCATIONAL OBJECTIVE: The most common finding in a newborn with Down syndrome is hypotonia which should prompt close evaluation and follow-up. Educational Objective: References: ]]
Approved	Approved::Yes
Keyword	WBRKeyword::Down syndrome
Linked Question	Linked::
Order in Linked Questions	LinkedOrder::