Wild-type (senile) ATTR amyloidosis surgery
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] ; Associate Editor(s)-in-Chief: Aditya Ganti M.B.B.S. [2]
Overview
Liver transplantation is the mainstay of treatment for wild-type ATTR amyloidosis.
Surgery
Liver transplantation is the mainstay of treatment for wild-type ATTR amyloidosis.[1]
- Transplantation replaces the main source of variant TTR with a source of normal-sequence TTR.
- This leads to gradual fibril reabsorption and disease stabilization, especially of neurologic complications.
References
- ↑ Puig-Carrion GD, Reyentovich A, Katz SD (September 2019). "Diagnosis and treatment of heart failure in hereditary transthyretin amyloidosis". Clin. Auton. Res. 29 (Suppl 1): 45–53. doi:10.1007/s10286-019-00629-5. PMC 6763576 Check
|pmc=
value (help). PMID 31452023.