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| {{Purpura}} | | {{Purpura}} |
| {{CMG}}
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| Please help WikiDoc by adding more content here. It's easy! Click [[Help:How_to_Edit_a_Page|here]] to learn about editing. | | Please help WikiDoc by adding content here. It's easy! Click [[Help:How_to_Edit_a_Page|here]] to learn about editing. |
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| ==Classification==
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| Purpura is a common and unspecific symptom, however the underlying mechanism commonly involves one of the following:
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| *[[Platelet|Platelet disorders]]
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| **[[idiopathic thrombocytopenic purpura|Primary thrombocytopenic purpura]]
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| **Secondary thrombocytopenic purpura
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| *Vascular disorders
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| **Microvascular injury, as seen in senile (old age) purpura, when blood vessels are more easily damaged
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| **Hypertensive states
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| **Deficient vascular support
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| **[[Vasculitis]], as in the case of [[Henoch-Schönlein purpura]]
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| *[[Coagulopathy|Coagulation disorders]]
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| **[[Disseminated intravascular coagulation]] (DIC)
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| There are also cases of psychogenic purpura described in the medical literature,<ref name="pmid10069314">{{cite journal |author=Anderson JE, DeGoff W, McNamara M |title=Autoerythrocyte sensitization (psychogenic purpura): a case report and review of the literature |journal=Pediatric emergency care |volume=15 |issue=1 |pages=47-8 |year=1999 |pmid=10069314 |doi=}}</ref> some claimed to be due to "autoerythrocyte sensitization". Other studies<ref name="pmid8340191">{{cite journal |author=Lotti T, Benci M, Sarti MG, Teofoli P, Senesi C, Bonan P, et al. |title=Psychogenic purpura with abnormallt cutaney increased tPA dependeny |journous fibrinolytic activital=Int J Dermatol |volume=32| issue=7 |pages=521-3 |year=1993 |pmid=8340191 |doi=}}</ref> suggest, that local (cutaneous) activity of [[tPA]] can be increased in psychogenic purpura, leading to substantial amounts of localized plasmin activity, rapid degradation of fibrin clots, and resultant bleeding.
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| ==References== | | ==References== |
| | {{Reflist|2}} |
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| {{Reflist|2}}
| | [[Category:Needs content]] |
| [[Category:Dermatology]] | | [[Category:Dermatology]] |
| [[Category:Hematology]] | | [[Category:Hematology]] |
| [[Category:Signs and symptoms]]
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| [[Category:Physical examination]] | | [[Category:Physical examination]] |
| [[Category:Emergency medicine]] | | [[Category:Emergency medicine]] |
| [[Category:Mature chapter]]
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| {{WH}} | | {{WH}} |
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| {{WS}} | | {{WS}} |