Sandbox: Kaposi: Difference between revisions

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Macular stage:
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Thin-walled, angulated vessels throughout dermis, with hemosiderin and plasma cell infiltrate
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Patch stage:
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Angulated lumina that dissect dermal collagen
! style="background: #4479BA; width: 200px;" | {{fontcolor|#FFF|Clincal Stage  }}
Vessels may proliferate around well-developed round venules (premonitory sign)
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Angiomatoid vascular spaces with red blood cells are surrounded by spindle cells in short fascicles
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Tumor stage:
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Solid nodules with extensive spindle cells and red blood cells in slit-like lumina
'''Macular stage'''
No/rare mitotic activity or atypia
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Lymphangioma-like variant:
* Thin vessel wall
Thin, angulated vessels with no red blood cells
* Angulated vessels throughout dermis
* Plasma cell and hemosiderin infiltrates
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'''Patch stage'''
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* Angulated lumina that dissect dermal collagen
* Premonitory sign
* Spindle cells surround angiomatoid vascular spaces filled with RBC
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'''Tumor stage'''
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* Solid nodules  
* The presence of spindle cells and red blood cells in a slit-like lumina
* Abscence of cellular atypia or mitotic activity  
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'''Lymphangioma-like variant'''
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* Thin walled, angulated vessels
* Absence of red blood cells
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Latest revision as of 17:21, 19 January 2016

Clincal Stage Histologic Features

Macular stage

  • Thin vessel wall
  • Angulated vessels throughout dermis
  • Plasma cell and hemosiderin infiltrates

Patch stage

  • Angulated lumina that dissect dermal collagen
  • Premonitory sign
  • Spindle cells surround angiomatoid vascular spaces filled with RBC

Tumor stage

  • Solid nodules
  • The presence of spindle cells and red blood cells in a slit-like lumina
  • Abscence of cellular atypia or mitotic activity

Lymphangioma-like variant

  • Thin walled, angulated vessels
  • Absence of red blood cells