Hemophagocytic lymphohistiocytosis natural history, complications and prognosis: Difference between revisions
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==Prognosis== | ==Prognosis== | ||
* Without treatment, most people with familial hemophagocytic lymphohistiocytosis survive only a few months. | * Secondary HLH in some individuals may be self-limited because patients are able to fully recover after having received only supportive medical treatment. However, long-term remission without the use of cytotoxic and immune-suppressive therapies is unlikely in the majority of adults with HLH and in those with CNS involvement. | ||
* Without treatment, most people with familial hemophagocytic lymphohistiocytosis survive only a few months. | |||
==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} | ||
[[Category:Pediatrics]] | [[Category:Pediatrics]] | ||
[[Category:Hematology]] | [[Category:Hematology]] | ||
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Latest revision as of 13:12, 23 June 2016
Hemophagocytic lymphohistiocytosis Microchapters |
Differentiating Hemophagocytic lymphohistiocytosis from other Diseases |
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Diagnosis |
Treatment |
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Hemophagocytic lymphohistiocytosis natural history, complications and prognosis On the Web |
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Blogs on Hemophagocytic lymphohistiocytosis natural history, complications and prognosis |
Directions to Hospitals Treating Hemophagocytic lymphohistiocytosis |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
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Overview
Natural History
Complications
- Complications include
- Immunodeficiency
- Blindness
- Coma
- Leukemia and lymphoma
- Posterior reversible encephalopathy syndrome
Prognosis
- Secondary HLH in some individuals may be self-limited because patients are able to fully recover after having received only supportive medical treatment. However, long-term remission without the use of cytotoxic and immune-suppressive therapies is unlikely in the majority of adults with HLH and in those with CNS involvement.
- Without treatment, most people with familial hemophagocytic lymphohistiocytosis survive only a few months.