Linear IgA bullous dermatosis: Difference between revisions
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{{CMG}}; {{AE}} {{KS}} | {{CMG}}; {{AE}} {{KS}} | ||
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==Overview== | ==Overview== | ||
'''Linear IgA bullous dermatosis''' (also known as "Linear IgA dermatosis") is frequently associated with medication exposure, especially [[vancomycin]], with men and women being equally affected.<ref name="Andrews">James, William; Berger, Timothy; Elston, Dirk (2005). ''Andrews' Diseases of the Skin: Clinical Dermatology''. (10th ed.). Saunders. ISBN 0-7216-2921-0.</ref>{{rp|135}} It was first described by [[Tadeusz Chorzelski]] in 1979. Linear IgA dermatosis is a rare immune-mediated blistering skin disease that may be divided into two types:<ref name="Fitz2">Freedberg, et al. (2003). ''Fitzpatrick's Dermatology in General Medicine''. (6th ed.). McGraw-Hill. ISBN 0-07-138076-0.</ref>{{rp|587}} | '''Linear IgA bullous dermatosis''' (also known as "Linear IgA dermatosis") is frequently associated with medication exposure, especially [[vancomycin]], with men and women being equally affected.<ref name="Andrews">James, William; Berger, Timothy; Elston, Dirk (2005). ''Andrews' Diseases of the Skin: Clinical Dermatology''. (10th ed.). Saunders. ISBN 0-7216-2921-0.</ref>{{rp|135}} It was first described by [[Tadeusz Chorzelski]] in 1979. Linear IgA dermatosis is a rare immune-mediated blistering skin disease that may be divided into two types:<ref name="Fitz2">Freedberg, et al. (2003). ''Fitzpatrick's Dermatology in General Medicine''. (6th ed.). McGraw-Hill. ISBN 0-07-138076-0.</ref>{{rp|587}} | ||
* ''Adult linear IgA disease'' is an acquired, autoimmune blistering disease that may present with a clinical pattern of vesicles indistinguishable from dermatitis herpetiformis, or with vesicles and bullae in a bullous pemphigoid-like appearance. <ref name="Andrews"/> | * ''Adult linear IgA disease'' is an acquired, autoimmune blistering disease that may present with a clinical pattern of vesicles indistinguishable from dermatitis herpetiformis, or with vesicles and bullae in a bullous pemphigoid-like appearance. <ref name="Andrews"/> | ||
* ''Childhood linear IgA disease'' (also known as "Chronic bullous disease of childhood") is an acquired, self-limited bullous disease that may begin by the time the patient is age 2 to 3 and usually remits by age 13. <ref name="Andrews"/> | * ''Childhood linear IgA disease'' (also known as "Chronic bullous disease of childhood") is an acquired, self-limited bullous disease that may begin by the time the patient is age 2 to 3 and usually remits by age 13. <ref name="Andrews"/> | ||
==Historical Perspective== | |||
==Classification== | |||
==Pathophysiology== | |||
==Causes== | |||
==Differentiating Linear IgA bullous dermatosis from other Diseases== | |||
==Epidemiology and Demographics== | |||
===Age=== | |||
===Gender=== | |||
===Race=== | |||
==Risk Factors== | |||
== Natural History, Complications and Prognosis== | |||
==Diagnosis== | ==Diagnosis== | ||
===Diagnostic Criteria=== | |||
===Symptoms=== | |||
===Physical Examination=== | ===Physical Examination=== | ||
====Skin==== | ====Skin==== | ||
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Image:Childhood linear IgA disease21.jpg|Childhood linear IgA disease. <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/ Adapted from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite web | title = Dermatology Atlas | url = http://www.atlasdermatologico.com.br/}}</ref></SMALL></SMALL> | Image:Childhood linear IgA disease21.jpg|Childhood linear IgA disease. <SMALL><SMALL>''[http://www.atlasdermatologico.com.br/ Adapted from Dermatology Atlas.]''<ref name="Dermatology Atlas">{{Cite web | title = Dermatology Atlas | url = http://www.atlasdermatologico.com.br/}}</ref></SMALL></SMALL> | ||
</gallery> | </gallery> | ||
=== Laboratory Findings === | |||
===Imaging Findings=== | |||
=== Other Diagnostic Studies === | |||
== Treatment == | |||
=== Medical Therapy === | |||
=== Surgery === | |||
=== Prevention === | |||
==See also== | ==See also== | ||
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{{reflist}} | {{reflist}} | ||
[[Category: | [[Category:Rheumatology]] | ||
[[Category: | [[Category:Needs content]] | ||
{{Vesiculobullous disease}} | {{Vesiculobullous disease}} |
Latest revision as of 19:49, 5 July 2016
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Kiran Singh, M.D. [2]
Synonyms and keywords:
Overview
Linear IgA bullous dermatosis (also known as "Linear IgA dermatosis") is frequently associated with medication exposure, especially vancomycin, with men and women being equally affected.[1]:135 It was first described by Tadeusz Chorzelski in 1979. Linear IgA dermatosis is a rare immune-mediated blistering skin disease that may be divided into two types:[2]:587
- Adult linear IgA disease is an acquired, autoimmune blistering disease that may present with a clinical pattern of vesicles indistinguishable from dermatitis herpetiformis, or with vesicles and bullae in a bullous pemphigoid-like appearance. [1]
- Childhood linear IgA disease (also known as "Chronic bullous disease of childhood") is an acquired, self-limited bullous disease that may begin by the time the patient is age 2 to 3 and usually remits by age 13. [1]
Historical Perspective
Classification
Pathophysiology
Causes
Differentiating Linear IgA bullous dermatosis from other Diseases
Epidemiology and Demographics
Age
Gender
Race
Risk Factors
Natural History, Complications and Prognosis
Diagnosis
Diagnostic Criteria
Symptoms
Physical Examination
Skin
Trunk And Extremities
-
Childhood linear IgA disease. Adapted from Dermatology Atlas.[3]
-
Childhood linear IgA disease. Adapted from Dermatology Atlas.[3]
-
Childhood linear IgA disease. Adapted from Dermatology Atlas.[3]
-
Childhood linear IgA disease. Adapted from Dermatology Atlas.[3]
-
Childhood linear IgA disease. Adapted from Dermatology Atlas.[3]
-
Childhood linear IgA disease. Adapted from Dermatology Atlas.[3]
-
Childhood linear IgA disease. Adapted from Dermatology Atlas.[3]
-
Childhood linear IgA disease. Adapted from Dermatology Atlas.[3]
-
Childhood linear IgA disease. Adapted from Dermatology Atlas.[3]
-
Childhood linear IgA disease. Adapted from Dermatology Atlas.[3]
-
Childhood linear IgA disease. Adapted from Dermatology Atlas.[3]
-
Childhood linear IgA disease. Adapted from Dermatology Atlas.[3]
-
Childhood linear IgA disease. Adapted from Dermatology Atlas.[3]
-
Childhood linear IgA disease. Adapted from Dermatology Atlas.[3]
-
Childhood linear IgA disease. Adapted from Dermatology Atlas.[3]
-
Childhood linear IgA disease. Adapted from Dermatology Atlas.[3]
-
Childhood linear IgA disease. Adapted from Dermatology Atlas.[3]
-
Childhood linear IgA disease. Adapted from Dermatology Atlas.[3]
-
Childhood linear IgA disease. Adapted from Dermatology Atlas.[3]
-
Childhood linear IgA disease. Adapted from Dermatology Atlas.[3]
-
Childhood linear IgA disease. Adapted from Dermatology Atlas.[3]
Laboratory Findings
Imaging Findings
Other Diagnostic Studies
Treatment
Medical Therapy
Surgery
Prevention
See also
- Skin lesion
- List of cutaneous conditions
- List of target antigens in pemphigoid
- List of immunofluorescence findings for autoimmune bullous conditions
References
- ↑ 1.0 1.1 1.2 James, William; Berger, Timothy; Elston, Dirk (2005). Andrews' Diseases of the Skin: Clinical Dermatology. (10th ed.). Saunders. ISBN 0-7216-2921-0.
- ↑ Freedberg, et al. (2003). Fitzpatrick's Dermatology in General Medicine. (6th ed.). McGraw-Hill. ISBN 0-07-138076-0.
- ↑ 3.00 3.01 3.02 3.03 3.04 3.05 3.06 3.07 3.08 3.09 3.10 3.11 3.12 3.13 3.14 3.15 3.16 3.17 3.18 3.19 3.20 "Dermatology Atlas".