Shigellosis other diagnostic studies: Difference between revisions
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{{Shigellosis}} | {{Shigellosis}} | ||
{{CMG}} '''Associate Editor(s)-In-Chief:''' [[User:YazanDaaboul|Yazan Daaboul]]; [[User:Sergekorjian|Serge Korjian]] | |||
==Overview== | |||
Other diagnostic studies, such as [[enzyme-linked immunoassay]] (ELISA), [[polymerase chain reaction]] (PCR), or colon/rectal biopsies, are not always necessary but may be required for the diagnosis of shigellosis in the minority of patients, such as high risk patients who are hospitalized and in need of urgent management). | |||
==Other Diagnostic Studies== | |||
===Enzyme-linked Immunoassay (ELISA)=== | |||
*Detection of ''S. dysenteriae'' type 1 toxin in stools | |||
===Polymerase Chain Reaction (PCR)=== | |||
*Detection of virulence genes of ''Shigella'' | |||
**''ipaH'' gene | |||
**''virF'' gene | |||
**''virA'' gene | |||
===Colonic or Rectal Biopsy=== | |||
On microscopic histopathological analysis, the following findings may be observed from samples of the [[colon]], [[rectum]], and occasionally the distal [[ileum]]: | |||
*PMN infiltration | |||
*Formation of patchy inflammatory pseudomembrane | |||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} | ||
[[Category: | [[Category:Disease]] | ||
[[Category:Gastroenterology]] | [[Category:Gastroenterology]] | ||
{{WikiDoc Help Menu}} | {{WikiDoc Help Menu}} | ||
{{WikiDoc Sources}} | {{WikiDoc Sources}} | ||
Latest revision as of 19:04, 18 September 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-In-Chief: Yazan Daaboul; Serge Korjian
Overview
Other diagnostic studies, such as enzyme-linked immunoassay (ELISA), polymerase chain reaction (PCR), or colon/rectal biopsies, are not always necessary but may be required for the diagnosis of shigellosis in the minority of patients, such as high risk patients who are hospitalized and in need of urgent management).
Other Diagnostic Studies
Enzyme-linked Immunoassay (ELISA)
- Detection of S. dysenteriae type 1 toxin in stools
Polymerase Chain Reaction (PCR)
- Detection of virulence genes of Shigella
- ipaH gene
- virF gene
- virA gene
Colonic or Rectal Biopsy
On microscopic histopathological analysis, the following findings may be observed from samples of the colon, rectum, and occasionally the distal ileum:
- PMN infiltration
- Formation of patchy inflammatory pseudomembrane